Breathwork-induced psychedelic experiences modulate neural dynamics.
Evan Lewis-Healey, Enzo Tagliazucchi, Andrés Canales-Johnson, Tristan A Bekinschtein
Cerebral Cortex August 1, 2024 DOI: 10.1093/cercor/bhae347 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Observational cohort Peer reviewed |
|---|---|
| Sample size | 14 |
| Population | Novice participants |
| Intervention | Breathwork |
| Duration | 28 days, with sessions of 20, 40, or 60 minutes |
| Topics | Altered states of consciousness Breathwork |
| Keywords | Neural complexity Neurophenomenology Psychedelics |
| Citations | 27 |
| Key findings | Psychedelic-like subjective experiences during breathwork were associated with increased neural Lempel-Ziv complexity and changes in the aperiodic exponent of the power spectral density. |
Abstract
Breathwork is an understudied school of practices involving intentional respiratory modulation to induce an altered state of consciousness (ASC). We simultaneously investigate the phenomenological and neural dynamics of breathwork by combining Temporal Experience Tracing, a quantitative methodology that preserves the temporal dynamics of subjective experience, with low-density portable EEG devices. Fourteen novice participants completed a course of up to 28 breathwork sessions-of 20, 40, or 60 min-in 28 days, yielding a neurophenomenological dataset of 301 breathwork sessions. Using hypothesis-driven and data-driven approaches, we found that "psychedelic-like" subjective experiences were associated with increased neural Lempel-Ziv complexity during breathwork. Exploratory analyses showed that the aperiodic exponent of the power spectral density-but not oscillatory alpha power-yielded similar neurophenomenological associations. Non-linear neural features, like complexity and the aperiodic exponent, neurally map both a multidimensional data-driven composite of positive experiences, and hypothesis-driven aspects of psychedelic-like experience states such as high bliss.
In the evidence
This study is part of the evidence base for a synthesis in the library. Here is how each one recorded it.
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State of the evidence: Breathwork Supports
Psychedelic-like subjective experiences during breathwork were associated with increased neural Lempel-Ziv complexity, and exploratory analyses linked the aperiodic exponent of the power spectral density to positive and bliss-like experience states.
Synthesized
Comparable studies
Other observational and cohort studies on breathwork, most cited first.
Citations in the library
Cited by 20
- An Overview of Neurophenomenological Approaches to Meditation and Their Relevance to Clinical Research. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging April 1, 2025
- Classification schemes of altered states of consciousness. Neuroscience & Biobehavioral Reviews August 1, 2025
- Integrated Phenomenology and Brain Connectivity Demonstrate Changes in Nonlinear Processing in Jhana Advanced Meditation. Journal of Cognitive Neuroscience May 14, 2025
- The ConNECT approach: toward a comprehensive understanding of meaningful interpersonal moments in psychotherapy and beyond. Frontiers in Human Neuroscience 2025
- The entropic brain today Brain December 12, 2025
and 15 more in the library
Cites 79
- Interoceptive inference, emotion, and the embodied self Trends in Cognitive Sciences October 12, 2013
- Psilocybin can occasion mystical-type experiences having substantial and sustained personal meaning and spiritual significance Psychopharmacology July 7, 2006
- Neural correlates of consciousness: progress and problems Nature Reviews Neuroscience April 20, 2016
- Mind the Hype: A Critical Evaluation and Prescriptive Agenda for Research on Mindfulness and Meditation Perspectives on Psychological Science October 10, 2017
- Trial of Psilocybin versus Escitalopram for Depression New England Journal of Medicine April 14, 2021
and 74 more in the library