The influence of mindfulness meditation combined with progressive muscle relaxation training on the clinical efficacy and quality of life of patients with sarcopenia receiving haemodialysis: a randomised controlled trial.
Yong-Yao Wu, Yi-Yi Gao, Jing-Qiao Wang, Chao Zhang, Peng-Jie Xu, Jiang Liu, Ri-Zhen Yu, Hao-Jie Zhang
BMC Complementary Medicine and Therapies May 17, 2024 DOI: 10.1186/s12906-024-04485-3 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Randomized controlled trial Peer reviewed |
|---|---|
| Sample size | 49 |
| Population | Patients with sarcopenia receiving maintenance haemodialysis |
| Interventions | Mindfulness meditation Progressive muscle relaxation training |
| Duration | 12-week intervention |
| Topics | Meditation |
| Keywords | Maintenance haemodialysis Mindfulness meditation Progressive muscle relaxation Quality of life Uremic sarcopenia |
| Citations | 14 |
| Key findings | Mindfulness meditation combined with progressive muscle relaxation training improved exercise capacity and quality of life in patients with sarcopenia on maintenance haemodialysis after 12 weeks. |
Abstract
To study the effect of mindfulness meditation combined with progressive muscle relaxation training on the clinical efficacy and quality of life in patients with sarcopenia receiving maintenance haemodialysis (MHD). Eligible patients with sarcopenia in our hospital were randomly assigned to a control group (n = 24) and an intervention group (n = 25). The control group received conventional dialysis treatment, while the intervention group underwent mindfulness meditation combined with progressive muscle relaxation training during the interdialysis period in addition to conventional dialysis treatment. The effect of the intervention was evaluated after 12 weeks. There were no significant differences in the baseline values of various parameters between the two groups. Exercise capacity (sit-to-stand test,handgrip,time to 10 sit-ups) significantly improved in the intervention group after 12 weeks (32.68 ± 8.32 vs 26.50 ± 6.83; 37.42 ± 10.12 vs 28.12 ± 8.51; 19.8 ± 5.40 vs 25.29 ± 7.18) (p 0.05). When compared with the control group, the intervention group showed significant improvements in 10 dimensions of exercise capacity and KDQOLTM scores for physical function, role-physical, general health, energy, symptom/problem list, sleep, DSE, pain, cognitive function, emotional well-being and patient PS after 12 weeks (61.30 ± 5.38 vs 42.98 ± 5.73; 57.50 ± 3.55 vs 50.70 ± 3.62) (p < 0.05). Some inflammatory markers, such as the levels of interleukin-6 and high-sensitivity C-reactive protein (30.29 ± 2.96 vs 17.65 ± 3.22; 8.93 ± 0.99 vs 3.02 ± 0.34), showed a decrease during the intervention, while albumin and prealbumin levels were significantly increased compared with the baseline (30.62 ± 1.65 vs 35.60 ± 1.68; 0.32 ± 0.05 vs 0.44 ± 0.07) (p < 0.05). Combined intervention training can improve the motor ability and quality of life of patients with sarcopenia within a short period of time.
Comparable studies
Other randomized controlled trials on meditation, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| Alterations in Brain and Immune Function Produced by Mindfulness Meditation Healthy employees in a work environment | 2003 | Randomized controlled trial | n = 41 |
| Prevention of relapse/recurrence in major depression by mindfulness-based cognitive therapy. Recovered recurrently depressed patients | 2000 | Randomized controlled trial | n = 145 |
| Open hearts build lives: Positive emotions, induced through loving-kindness meditation, build consequential personal resources. Working adults | 2008 | Randomized controlled trial | n = 139 |
| Short-term meditation training improves attention and self-regulation Undergraduate Chinese students | 2007 | Randomized controlled trial | n = 40 |
| Mindfulness-Based Cognitive Therapy for Depression: Replication and Exploration of Differential Relapse Prevention Effects. Recovered recurrently depressed patients | 2004 | Randomized controlled trial | n = 73 |
Citations in the library
Cited by 5
- Effects of mindfulness meditation combined with progressive muscle relaxation on sleep disorders, anxiety, and depression in patients with sarcopenia undergoing hemodialysis. Frontiers in Psychiatry 2025
- Effects of mindfulness meditation on blood pressure and quality of life in patients with intradialytic hypertension during haemodialysis: A randomised controlled trial. Complementary Therapies in Medicine November 1, 2025
- The Role of Mindfulness in Hemodialysis Patients: A Scoping Review Mindfulness September 9, 2026
- Exploring the Impact of Sensory Conflict on State Mindfulness in VR Meditation Training International Conference on Human Factors in Computing Systems April 13, 2026
- Effect of meditation and prenatal education on fear and confidence in vaginal delivery Frontiers in Public Health December 10, 2025
Cites 9
- Mindfulness Meditation and Psychopathology Annual Review of Clinical Psychology December 11, 2018
- Mindfulness Meditation for Substance Use Disorders: A Systematic Review Substance Abuse October 1, 2009
- A Randomized Controlled Trial of Mindfulness-Based Cognitive Therapy for Treatment-Resistant Depression Psychotherapy and Psychosomatics 2016
- Mindfulness-Based Interventions for Physical Conditions: A Narrative Review Evaluating Levels of Evidence ISRN Psychiatry November 14, 2012
- Long-term Effects of a Brief Mindfulness Intervention Versus a Health Enhancement Program for Treating Depression and Anxiety in Patients Undergoing Hemodialysis: A Randomized Controlled Trial. Can J Kidney Health Dis March 4, 2022
and 4 more in the library