A new mindfulness and psycho-educative program for treatment of brain fatigue, evaluated after an acquired brain injury and multiple sclerosis.
Gustaf Glavå, Lars Rönnbäck, Birgitta Johansson
Health psychology and behavioral medicine 2025 DOI: 10.1080/21642850.2025.2502039 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Randomized pilot study Qualitative Peer reviewed |
|---|---|
| Sample size | 32 |
| Population | Participants with long-term fatigue after acquired brain injury or multiple sclerosis |
| Intervention | Brain Fatigue and Mindfulness program |
| Duration | Six biweekly group meetings |
| Topics | Meditation |
| Keywords | Fatigue Acquired brain injury Multiple sclerosis Neurorehabilitation |
| Key points | The Brain Fatigue and Mindfulness program significantly reduced brain fatigue and anxiety compared to a waitlist control group. |
Abstract
Background: Fatigue is a common long-term problem after illnesses affecting the brain, having substantial impact on work ability, social activities, and quality of life. Treatment has been requested in the healthcare and by patients. The aim of this randomized pilot study is to evaluate a new Brain Fatigue and Mindfulness program (BF-M) for participants suffering from long-term fatigue after an acquired brain injury or Multiple Sclerosis. BF-M consists of six biweekly group meetings. Meditation is practiced, knowledge is imparted about fatigue and participants have time to share and discuss common issues.
Methods: A mixed method research design is used with quantitative and qualitative methods. Sixteen participants completed BF-M and 16 controls on waitlist responded to questionnaires before and after the intervention.
Results: After the program, the BF-M group had a significant reduction in BF and anxiety compared to the controls. The analysis of 13 interviews with BF-M participants suggested that: (1) BF-M became a space for the participants to exchange and share experiences associated with BF; (2) the participants felt more understood and less alone; and (3) they learned how to better understand and live with brain fatigue.
Conclusions: This study showed that BF-M may reduce brain fatigue and help participants to better manage their difficulties. Based on this pilot study, we suggest that BF-M may be considered as a rehabilitation option for brain fatigue. However, more confirmatory research with larger and different patient groups is needed.
Comparable studies
Other randomized controlled trials on meditation, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| Alterations in Brain and Immune Function Produced by Mindfulness Meditation Healthy employees in a work environment | 2003 | Randomized controlled trial | n = 41 |
| Prevention of relapse/recurrence in major depression by mindfulness-based cognitive therapy. Recovered recurrently depressed patients | 2000 | Randomized controlled trial | n = 145 |
| Open hearts build lives: Positive emotions, induced through loving-kindness meditation, build consequential personal resources. Working adults | 2008 | Randomized controlled trial | n = 139 |
| Short-term meditation training improves attention and self-regulation Undergraduate Chinese students | 2007 | Randomized controlled trial | n = 40 |
| Mindfulness-Based Cognitive Therapy for Depression: Replication and Exploration of Differential Relapse Prevention Effects. Recovered recurrently depressed patients | 2004 | Randomized controlled trial | n = 73 |
Citations in the library
Cites 13
- What defines mindfulness-based programs? The warp and the weft Psychological Medicine December 29, 2016
- Competence in Teaching Mindfulness-Based Courses: Concepts, Development and Assessment Mindfulness September 21, 2011
- Mindfulness-based stress reduction (MBSR) improves long-term mental fatigue after stroke or traumatic brain injury Brain Injury July 13, 2012
- Potential treatment mechanisms in a mindfulness‐based intervention for people with progressive multiple sclerosis British Journal of Health Psychology May 30, 2016
- Therapeutic Effects of Meditation, Yoga, and Mindfulness-Based Interventions for Chronic Symptoms of Mild Traumatic Brain Injury: A Systematic Review and Meta-Analysis. Applied Psychology: Health and Well-Being November 2, 2020
and 8 more in the library