Beyond consciousness: Ethical, legal, and social issues in human brain organoid research and application.
Masanori Kataoka, Takuya Niikawa, Naoya Nagaishi, Tsung-Ling Lee, Alexandre Erler, Julian Savulescu, Tsutomu Sawai
European journal of cell biology March 1, 2025 DOI: 10.1016/j.ejcb.2024.151470 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Review Peer reviewed |
|---|---|
| Keywords | Biocomputing Brain organoid Chimera Elsi Ethics Public engagement |
| Citations | 22 |
| Key findings | Human brain organoid research raises diverse ethical, legal, and social issues that vary by application and require a multidisciplinary approach. |
Abstract
This study aims to provide a comprehensive review of the ethical, legal and social issues in human brain organoid research, with a view to different types of research and applications: in vitro research, transplantation into non-human animals, and biocomputing. Despite the academic and societal attention on the possibility that human brain organoids may be conscious, we have identified diverse issues in human brain organoid research and applications. To guide the complex terrain of human brain organoid research and applications, a multidisciplinary approach that integrates ethical, legal, and social perspectives is essential.
Citations in the library
Cites 26
- Are There Islands of Awareness? Trends in Neurosciences December 10, 2019
- Potential Consciousness of Human Cerebral Organoids: on Similarity-Based Views in Precautionary Discourse Neuroethics September 17, 2023
- Ethical Implications in Making Use of Human Cerebral Organoids for Investigating Stress—Related Mechanisms and Disorders Cambridge Quarterly of Healthcare Ethics February 17, 2023
- Non-Human Moral Status: Problems with Phenomenal Consciousness. AJOB Neuroscience December 7, 2022
- An assessment of the moral value of neuronal cell models and brain organoids Molecular Psychology Brain Behavior and Society July 10, 2023
and 21 more in the library