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Tsutomu Sawai

4 papers in the library · 29 citations · publishing 2023-2025

Papers

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Beyond consciousness: Ethical, legal, and social issues in human brain organoid research and application.

European journal of cell biology March 1, 2025 Masanori Kataoka, Takuya Niikawa, Naoya Nagaishi et al. 22 citations

This study aims to provide a comprehensive review of the ethical, legal and social issues in human brain organoid research, with a view to different types of research and applications: in vitro research, transplantation into non-human animals, and biocomputing. Despite the academic and societal attention on the possibility that human brain organoids may be conscious, we have identified diverse...

The Donation of Human Biological Material for Brain Organoid Research: The Problems of Consciousness and Consent.

Science and Engineering Ethics February 5, 2024 Masanori Kataoka, Christopher Gyngell, Julian Savulescu et al.

AbstractHuman brain organoids are three-dimensional masses of tissues derived from human stem cells that partially recapitulate the characteristics of the human brain. They have promising applications in many fields, from basic research to applied medicine. However, ethical concerns have been raised regarding the use of human brain organoids. These concerns primarily relate to the possibility...

The Ethics of Human Brain Organoid Transplantation in Animals.

Neuroethics October 4, 2023 Masanori Kataoka, Christopher Gyngell, Julian Savulescu et al.

In this paper, we outline how one might conduct a comprehensive ethical evaluation of human brain organoid transplantation in animals. Thus far, ethical concerns regarding this type of research have been assumed to be similar to those associated with other transplants of human cells in animals, and have therefore not received significant attention. The focus has been only on the welfare, moral...

DOI: 10.1007/s12152-023-09532-3 (opens in new tab) Full text (opens in new tab) Transplantation Chimeras Enhancement Consciousness +1