JAMA
June 19, 1967
Barry J. Materson
6 citations
THE usual oral dose (25μg to 150μg) of lysergic acid diethylamide (LSD) required for a desired psychedelic effect is far below that which causes other serious derangements directly attributable to its pharmacologic activity. Complications of the illicit oral use of the drug, despite larger doses, are also largely limited to its hallucinogenic and psychologic effect. Doses of 20μg/kg of body...
JAMA
August 8, 1966
J. Thomas Ungerleider
61 citations
The symptoms, diagnostic categories, and general characteristics of patients in 70 cases of adverse reactions to lysergic acid diethylamide tartrate (LSD) are varied. Psychiatric side effects ranged from depressive reaction to psychotic states. In all cases, LSD ingestion occurred separately and apart from medical-experimental and psychiatric-therapeutic models of LSD usage. Findings based on...
JAMA
August 8, 1966
J. Thomas Ungerleider
43 citations
The symptoms, diagnostic categories, and general characteristics of patients in 70 cases of adverse reactions to lysergic acid diethylamide tartrate (LSD) are varied. Psychiatric side effects ranged from depressive reaction to psychotic states. In all cases, LSD ingestion occurred separately and apart from medical-experimental and psychiatric-therapeutic models of LSD usage. Findings based on...
JAMA
April 11, 1966
Sidney Cohen
7 citations
This book attempts to set down, almost verbatim, the verbalizations of three subjects given LSD, psilocybin, sernyl, and a placebo. The drugs were administered in a single-blind fashion under conditions of sensory monotony, namely, listening to noise and looking at a glazed white dome for three hours. What the authors hoped to achieve was to eliminate the extraneous factors of setting and set...
JAMA
July 12, 1965
Donald E. Widmann
37 citations
The medical community was alarmed recently by the uncontrolled and somewhat-promiscuous use of "hallucinogens" in one of our major cities. The lay press contained many accounts suggesting the various hallucinogenic properties, but emphasized that the drugs seemed to provide the user with something of a mystic experience— what has been called "instant Zen." InThe Beyond Withinthe author places...
JAMA
January 11, 1965
Arnold M. Ludwig
55 citations
The use of hallucinogenic (psychotomimetic, dysleptic, psychedelic) substances to produce altered states of consciousness is not new,1-3but recently there has been increased interest and publicity given these agents. This renewed attention has been spurred by the discovery of several new substances, such as d-lysergic acid diethylamide (LSD), psilocybin, and psilocin, which have potencies far...
JAMA
March 7, 1964
Jonathan Cole, Martin M. Katz
16 citations
FOR MANY YEARS several pharmacologically similar drugs—lysergic acid diethylamide (LSD-25), psilocybin, and mescaline, among others—have been of special scientific interest. In volunteer subjects, they have been known to produce a variety of intense and unusual psychic effects. These include bizarre visual phenomena, ranging from a heightening of the apparent brightness or beauty of colored...
JAMA
March 7, 1964
Roy R. Grinker
16 citations
For several years, quietly and without publicity, several scientists have been studying the behavioral pharmacology of lysergic acid diethylamide (LSD-25), and lately psilocybin, on experimental animals and human subjects. The psychotic effects of these drugs have some but not complete similarity to the schizophrenic psychoses, which has resulted in their classification as psychomimetics. Yet...
JAMA
September 14, 1963
Dana L. Farnsworth
11 citations
An article on stramonium intoxication in this issue ofThe Journal(p 882) calls attention to a growing medical and social problem in this country—the ingestion of a number of drugs which have the common property of drastically altering sensory perception. The drugs all produce hallucinations. In addition to stramonium, the drugs include mescaline or peyote, lysergic acid diethylamide (LSD-25),...
JAMA
July 14, 1962
Sidney Cohen
65 citations
TWO DECADES AGO Hofmann ' accidentally discovered the hallucinogenic activity of d-lysergic acid diethylamide (LSD-25). Its ability to induce a model psychosis makes it an excellent laboratory device for the study of psychotic-like phenomena. LSD-25 has also been employed as an adjunct to psychotherapy because recall of repressed memories is enhanced and ego defensiveness to conflict laden...
JAMA
December 10, 1960
L. Lunsky
4 citations
Contributors to this volume include psychiatrists, psychologists, ethnologists, and sociologists. The purpose of the volume, as outlined in the introduction, is to promote effective communication by the give-and-take of lively discussions. Unfortunately, meaningful communication is infrequently achieved in this volume. The discussions are tangential and lack coherence. The experiments which are...