Annals of emergency medicine
June 30, 2025
Joshua C. Black, Karilynn M Rockhill, Evelyn J Fox et al.
4 citations
Oregon and Colorado have legalized possession of natural psychedelic drugs. We assessed if travel to use psychedelics in decriminalized states is occurring and compared the use patterns of travelers with nontravelers. The National Survey Investigating Hallucinogen Trends is a cross-sectional behavioral survey fielded from April to June 2024 to every US state. The survey asks whether individuals...
Annals of emergency medicine
May 1, 2025
Maeve Muldowney, Catherine R Counts, Madison C Maider et al.
2 citations
Acute behavioral disturbance is characterized by altered mental status and psychomotor agitation. Pharmacological sedation may be required, risking potential respiratory compromise. We compared the need for emergent airway support following administration of midazolam or ketamine to treat acute behavioral disturbance in the out-of-hospital setting. In this retrospective cohort study of patients...
Annals of emergency medicine
April 22, 2025
Daniel S Tsze, Nick Barrowman, Maala Bhatt
1 citation
Children with upper respiratory infections (URIs) have an increased risk of respiratory adverse events when undergoing operative anesthesia and in general populations of children receiving procedural sedation. It is unclear if children with URI undergoing emergency department (ED) sedation share the same increased risk. We aimed to determine if the presence of a URI in children undergoing ED...
Annals of emergency medicine
January 22, 2025
Neta Cohen, Nitai Levy, Jordanna H. Koppel et al.
2 citations
To cover pediatric emergency physicians' off-hours, third-year pediatric residents in Israel are trained for unsupervised administration of emergency department (ED) dissociative and deep sedation. We assessed the frequency of critical sedation events associated with resident-performed sedations. We conducted a retrospective chart review on all patients receiving intravenous sedation across 10...
Annals of emergency medicine
December 1, 2024
Mark W Simon, Heather A Olsen, Christopher O Hoyte et al.
12 citations
Psychedelic substances use is increasing in the United States (US). The approval of new psychedelic drugs and legalization of natural psychedelic substances will likely further increase exposures and subsequent adverse events. The study objective is to describe the clinical effects, therapies, and medical outcomes of patients with psychedelic exposures reported to US poison centers. We...
Annals of emergency medicine
October 1, 2024
Tommy Nguyen, Mo Mai, Amulya Choudhary et al.
11 citations
We aimed to assess and compare the analgesic efficacy and adverse effects of intravenous subdissociative-dose ketamine to nebulized ketamine in emergency department (ED) patients with acute painful conditions. We conducted a prospective, randomized, double-blind, double-dummy clinical trial in adult patients (ages 18 and older) with a numerical rating scale pain score of ≥5. We randomized...
Annals of emergency medicine
October 1, 2024
Jason T McMullan, Christopher A Droege, Kathleen M Chard et al.
5 citations
To evaluate if out-of-hospital administration of fentanyl and intranasal ketamine, compared to fentanyl alone, improves early pain control after injury. We conducted an out-of-hospital randomized, placebo-controlled, blinded, parallel group clinical trial from October 2017 to December 2021. Participants were male, aged 18 to 65 years, receiving fentanyl to treat acute traumatic pain prior to...
Annals of emergency medicine
September 1, 2020
Johanna J Nugteren-Van Lonkhuyzen, Dylan W de Lange, Antoinette J H P van Riel et al.
12 citations
We studied the severity of poisoning after exposure to low to moderate and high doses of 4-bromo-2,5-dimethoxyphenethylamine (2C-B). Patients for whom the Dutch Poisons Information Centre was consulted for 2C-B exposure from 2016 to 2018 were included in a prospective cohort study. Data were collected through telephone interviews with the physician or patient. Patients were categorized...
Annals of emergency medicine
July 1, 2012
Katharina E Hofer, Bettina Grager, Daniel Müller et al.
Methoxetamine, the N-ethyl derivative of ketamine, is a novel recreational drug that is not at present subject to restrictive regulations in most countries. To our knowledge, no case of methoxetamine abuse has been published to date in the scientific literature, and the only sources of information are illegal drug users' Web discussion forums. We report the first case of analytically confirmed...
Annals of emergency medicine
February 2007
Jonathan Rosenson, Craig Smollin, Karl A Sporer et al.
We describe the clinical characteristics of patients with ecstasy- (3,4-methylenedioxymethamphetamine [MDMA]) associated hyponatremia (serum sodium level <130 mmol/L) reported to the California Poison Control System during a 5-year period and determine whether a sex difference exists among patients with ecstasy-associated hyponatremia and hyponatremia-associated adverse outcomes. We performed a...
Annals of emergency medicine
June 1981
M M McCarron, B W Schulze, G A Thompson et al.
We describe four major and five minor clinical patterns of acute phencyclidine (PCP) intoxication and give the incidence of findings in each pattern. Major patterns were acute brain syndrome (248 cases; 24.8%), toxic psychosis (166 cases; 16.6%), catatonic syndrome (117 cases; 11.7%), and coma (106 cases; 10.6%). Minor patterns included lethargy or stupor (38 cases; 3.8%), and combinations of...