Addiction (Abingdon, England)
July 7, 2026
Johanna J Nugteren-Van Lonkhuyzen, Irma S Van den Hengel-Koot, Claudine C Hunault et al.
Data on the presence of new psychoactive substances (NPS) mainly originate from drug-checking, law enforcement and wastewater analysis sources, while data on NPS poisonings are scarce. In Europe, the documented incidence rate of NPS poisonings is highest in the Netherlands. We investigated temporal trends in NPS poisonings reported to the Dutch Poisons Information Center (DPIC) between 2012 and...
Clinical toxicology (Philadelphia, Pa.)
June 17, 2025
Antoinette J H P van Riel, Wouter M H van der Sanden, Laetitia M O de Kort
4 citations
Recreational ketamine use has increased in the last decades with incidental reports of urological complications. This study aimed to explore trends in the number of acute intoxications and urological complications from recreational ketamine use in the Netherlands. We retrospectively studied data from 2018 to 2024 from inquiries on ketamine toxicity to the Dutch Poisons Information Centre and...
Annals of emergency medicine
September 1, 2020
Johanna J Nugteren-Van Lonkhuyzen, Dylan W de Lange, Antoinette J H P van Riel et al.
12 citations
We studied the severity of poisoning after exposure to low to moderate and high doses of 4-bromo-2,5-dimethoxyphenethylamine (2C-B). Patients for whom the Dutch Poisons Information Centre was consulted for 2C-B exposure from 2016 to 2018 were included in a prospective cohort study. Data were collected through telephone interviews with the physician or patient. Patients were categorized...
Drug and Alcohol Dependence
December 1, 2015
Johanna J Nugteren-Van Lonkhuyzen, Antoinette J H P van Riel, Tibor M Brunt et al.
48 citations
Recently, the number of new psychoactive substances (NPS) appearing on the illicit drug market has shown a marked increase. Although many users perceive the risk of using NPS as medium or low, these substances can pose a serious health risk and several NPS have been implicated in drug-related deaths. In Europe, frequently detected NPS are 4-bromo-2,5-dimethoxyphenethylamine (2C-B),...