The European journal of neuroscience
June 1, 2026
Jenna Houff, Andrew Williams, Obie Allen et al.
Clinical trials suggest that a single dose of psilocybin may be an effective treatment for substance use disorders. Choice impulsivity is a value-based decision-making bias that predicts drug-intake escalation and is commonly associated with substance use disorders. The dorsomedial prefrontal cortex regulates choice impulsivity and is enriched with 5-HT2A receptors that mediate effects of...
The European journal of neuroscience
April 1, 2026
Maria Isabel Carreño-muñoz, Alessandra Ciancone Chama, Pegah Chehrazi et al.
In the neocortex, neuronal processing of sensory events is significantly influenced by their predictability. A common example is the suppression of responses to repetitive stimuli in sensory cortices, a phenomenon known as habituation. Within a sensory information stream, whenever a novel stimulus deviates from expectations, enhanced brain responses are observed. Mismatch negativity (MMN), the...
The European journal of neuroscience
May 1, 2025
Wolf Singer
2 citations
Several areas of cognitive neuroscience tackle traditional philosophical questions. Among the range of problems, two closely related issues will be addressed in more detail from both neurobiological and philosophical perspectives: the relationship between mind and matter and the nature of perception. Neuropsychological and neurophysiological studies are reviewed that examine the connection...
The European journal of neuroscience
October 1, 2024
Xiaotian Xu, Xiaoya Fan, Jiaoyang Dong et al.
4 citations
Virtual reality (VR)-guided motor imagery (MI) is a widely used approach for motor rehabilitation, especially for patients with severe motor impairments. Most approaches provide visual guidance from the first-person perspective (1PP). MI training with visual guidance from the third-person perspective (3PP) remains largely unexplored. We argue that 3PP MI training has its own advantages and can...
The European journal of neuroscience
September 1, 2024
Alessandra Buccella, Uri Maoz, Liad Mudrik
In recent decades, the neuroscientific community has moved from describing the neural underpinnings of mental phenomena-as characterized by experimental psychology and philosophy of mind-to attempting to redefine those mental phenomena based on neural findings. Nowadays, many are intrigued by the idea that neuroscience might provide the "missing piece" that would allow philosophers (and, to an...
The European journal of neuroscience
August 1, 2024
Francisco J Parada, Aitana Grasso-Cladera, Alejandra Rossi et al.
11 citations
The conventional medical paradigm often focuses on deficits and impairments, failing to capture the rich tapestry of experiences and abilities inherent in neurodiversity conditions. In this article, we introduce the 3E-Cognition perspective, offering a paradigm shift by emphasizing the dynamic interplay between the brain, body, and environment in shaping cognitive processes. The perspective...
The European journal of neuroscience
June 1, 2024
Connor J Haggarty, Anya K. Bershad, Mahesh K Kumar et al.
1 citation
The 3,4-methylenedioxymethamphetamine (MDMA) has long been used non-medically, and it is currently under investigation for its potential therapeutic benefits. Both uses may be related to its ability to enhance empathy, sociability, emotional processing and its anxiolytic effects. However, the neural mechanisms underlying these effects, and their specificity to MDMA compared to other stimulants,...
The European journal of neuroscience
April 1, 2024
David Zarka, C Cevallos, P Ruiz et al.
9 citations
The present study aimed to investigate the spontaneous dynamics of large-scale brain networks underlying mindfulness as a dispositional trait, through resting-state electroencephalography (EEG) microstates analysis. Eighteen participants had attended a standardized mindfulness-based stress reduction training (MBSR), and 18 matched waitlist individuals (CTRL) were recorded at rest while they...
The European journal of neuroscience
June 1, 2023
Alessandra Tafuro, Chiara Mazzi, Silvia Savazzi
The goal of this study was to investigate the neurophysiological correlates of visual awareness, with a specific focus on its event-related spectral perturbation (ERSP) features. To this aim, we tried to disentangle the proper neural correlates of consciousness (NCC) from other prerequisite and post-perceptual processing. To do so, we administered an orientation discrimination task, inducing a...
The European journal of neuroscience
November 1, 2022
Lau M Andersen, Mikkel C Vinding, Kristian Sandberg et al.
In the search for the neural correlates of consciousness, it is often assumed that there is a stable set within the relevant sensory modality. Within the visual modality, the debate has centred upon whether frontal or occipital activations are the best predictors of perceptual awareness. Although not accepted by all as definitive evidence, no-report and decoding studies have indicated that...
The European journal of neuroscience
June 1, 2022
Maëlan Q. Menétrey, Lukas Vogelsang, Michael H Herzog
Brain waves, determined by electrical and magnetic brain recordings (e.g., EEG and MEG), and fluctuating behavioral responses, determined by response time or accuracy measures, are frequently taken to support discrete perception. For example, it has been proposed that humans experience only one conscious percept per brain wave (e.g., during one alpha cycle). However, the proposed link between...
The European journal of neuroscience
March 1, 2022
Claudia Pascovich, Santiago Castro-Zaballa, Pedro A. M. Mediano et al.
16 citations
There is increasing evidence that the level of consciousness can be captured by neural informational complexity: for instance, complexity, as measured by the Lempel Ziv (LZ) compression algorithm, decreases during anaesthesia and non-rapid eye movement (NREM) sleep in humans and rats, when compared with LZ in awake and REM sleep. In contrast, LZ is higher in humans under the effect of...
The European journal of neuroscience
December 1, 2021
Francisco J Parada, Alejandra Rossi
48 citations
Recent technological advancements encompassed under the Mobile Brain/Body Imaging (MoBI) framework have produced exciting new experimental results linking mind, brain and behaviour. Nevertheless, novel hypotheses, measures and experimental paradigms are needed in order to tackle MoBI's ultimate goal: to model and understand cognition, behaviour and experience as it emerges and unfolds unto and...
The European journal of neuroscience
August 1, 2021
Jun-Ichi Uemura, Aiko Hoshino, Go Igarashi et al.
Conscious perception of a near-threshold (NT) stimulus is characterized by the pre- and post-stimulus brain state. However, the power of pre-stimulus neural oscillations and strength of post-stimulus cortical activity that lead to conscious perception have rarely been examined in individual cortical areas. This is because most previous electro- and magnetoencephalography (EEG and MEG,...
The European journal of neuroscience
February 1, 2020
Michiel van Elk, Lukas Snoek
The neural substrates of religious belief and experience are an intriguing though contentious topic. Here, we had the unique opportunity to establish the relation between validated measures of religiosity and gray matter volume in a large sample of participants (N = 211). In this registered report, we conducted a confirmatory voxel-based morphometry analysis to test three central hypotheses...
The European journal of neuroscience
June 1, 2017
Hector Vargas-Perez, Taryn E Grieder, Ryan Ting-A-Kee et al.
21 citations
Despite several studies suggesting the therapeutic use of 5-hydroxytryptamine receptors type 2A (5-HT2A ) agonists in the treatment of substance use disorders, the neurobiological basis accounting for such effects are still unknown. It has been observed that chronic exposure to drugs of abuse produces molecular and cellular adaptations in ventral tegmental area (VTA) neurons, mediated by...
The European journal of neuroscience
October 2004
Guadalupe Soria, Anna Castañé, Fernando Berrendero et al.
A2A adenosine and CB1 cannabinoid receptors are highly expressed in the central nervous system, where they modulate numerous physiological processes including adaptive responses to drugs of abuse. Both purinergic and cannabinoid systems interact with dopamine neurotransmission (through A2A and CB1 receptors, respectively). Changes in dopamine neurotransmission play an important role in...
The European journal of neuroscience
August 2004
Matthew N Hill, David J Froc, Christopher J Fox et al.
Adult male Long-Evans rats were administered the potent cannabinoid 1 receptor agonist HU-210 (100 microg/kg, i.p.) for 15 days continuously and their performance on a matching-to-place version of the Morris water maze was subsequently evaluated. Overall, experimental animals performed significantly worse initially on the reference memory component of this task, but their performance improved...
The European journal of neuroscience
August 2003
Andrew Harkin, Eamonn Shanahan, John P Kelly et al.
The effect of prior exposure to methylenedioxyamphetamine (MDA) on behavioural and neurochemical responses to fluoxetine were assessed in a rat model of antidepressant action. MDA (7.5 mg/kg, i.p.) was administered to rats twice daily for 4 consecutive days, and 4 weeks later the behavioural effect of fluoxetine (5 or 20 mg/kg; i.p. x 3) was examined in the modified rat forced-swimming test. In...
The European journal of neuroscience
April 1, 2001
N P Azari, J Nickel, G Wunderlich et al.
The commonsense view of religious experience is that it is a preconceptual, immediate affective event. Work in philosophy and psychology, however, suggest that religious experience is an attributional cognitive phenomenon. Here the neural correlates of a religious experience are investigated using functional neuroimaging. During religious recitation, self-identified religious subjects activated...
The European journal of neuroscience
February 2001
S C Azad, G Marsicano, I Eberlein et al.
This study investigated whether the nitric oxide pathway was involved in the central effects of Delta(9)-tetrahydrocannabinol (Delta(9)-THC), the major psychoactive constituent of cannabis sativa. Body temperature, nociception and locomotion were measured in neuronal nitric oxide synthase (nNOS) knock-out (KO) mice and wild-type (WT) controls after intraperitoneal application of Delta(9)-THC....