Journal of Chromatographic Science
November 15, 2025
Mahima Bansal, Estelle Miller, Rachael Sumner et al.
With the rising interest in therapeutic potential of microdosing lysergic acid diethylamide (LSD), accurate quantification and stability analysis are imperative for both scientific research and end-user safety. Currently, high throughput quantification of LSD in clinical microdosing formulations and community sourced microdosing samples remain a challenge due to the absence of fast analytical...
Journal of Chromatographic Science
October 26, 2020
Júlia Nagy, Tibor Veress
1 citation
The aim of this work was to investigate the applicability of a mathematical model developed for the description of supercritical fluid extraction (SFE) of cannabinoids from marijuana and hashish for liquid extraction of other substances. The mentioned model is applicable for dynamic SFE whose implementation is analogous to liquid-solid extraction in quasi-counter current mode. According to this...
Journal of Chromatographic Science
November 15, 2018
Norbert Rácz, Júlia Nagy, Wen Jiang et al.
12 citations
The goal of this work was to investigate and compare the selectivity of three different hydrophilic interaction liquid chromatography (HILIC) charge modulated amide columns, iHILIC®-Fusion, iHILIC®-Fusion(+) and iHILIC®-Fusion(P), for analysis of compounds in hallucinogen mushrooms. An extract of a truffle-like fungus containing psilocin, psilocybin and baeocystin was chosen as test material....
Journal of Chromatographic Science
July 12, 2016
B. Duffau, Cristian Camargo, M. Kogan et al.
Use of unauthorized synthetic drugs is a serious, forensic, regulatory and public health issue. In this scenario, consumption of drug-impregnated blotters is very frequent. For decades, blotters have been generally impregnated with the potent hallucinogen known as lysergic acid diethylamide (LSD); however, since 2013 blotter stamps with N-2 methoxybenzyl-substituted phenylethylamine...
Journal of Chromatographic Science
October 1, 2010
Tamer Awad, Tarek Belal, Hadir M Maher et al.
Three regioisomeric 3,4-methylenedioxyphenethylamines having the same molecular weight and major mass spectral fragments of equal mass have been reported as drugs of abuse in forensic studies in recent years. These compounds are 3,4-methylenedioxy-N-ethylamphetamine (MDEA), 3,4-methylenedioxy-N,N-dimethylamphetamine (MDMMA), and N-methyl-1-(3,4-methylenedioxyphenyl)-2-butanamine (MBDB). A...
Journal of Chromatographic Science
May 1, 2007
A. L. Thigpen, Jack DeRuiter, Charles R. Clark
9 citations
Three regioisomeric 3,4-methylenedioxyphenethylamines having the same molecular weight and major mass spectral fragments of equal mass have been reported as drugs of abuse in forensic studies in recent years. These compounds are 3,4-methylenedioxy-N-ethylamphetamine (MDEA), 3,4-methylenedioxy-N-N-dimethylamphetamine (MDMMA), and N-methyl-1-(3,4-methylenedioxyphenyl)-2-butanamine (MBDB). The...
Journal of Chromatographic Science
May 1, 1974
Albert R. Sperling
10 citations
An identification of LSD is presented utilizing a combination of thin-layer chromatography and gas chromatography. In the gas chromatographic identification, the trimethylsilyl derivative is prepared.
Journal of Chromatographic Science
1973
John D. Wittwer, J. H. Kluckhohn
46 citations
This paper presents a procedure to analyze d-lysergic acid diethylamide (LSD), which is probably the most widely abused of the hallucinogenic drugs. This procedure incorporates one simple preliminary step to extract LSD from illicit preparations prior to analysis by high speed LC.
Journal of Chromatographic Science
1973
Ellen M. Faed, W. R. Mcleod
19 citations
Journal Article A Urine Screening Test for Lysergide (LSD-25) Get access E. M. Faed, M.Sc, E. M. Faed, M.Sc Search for other works by this author on: Oxford Academic PubMed Google Scholar W. R. McLeod, M.D. W. R. McLeod, M.D. Search for other works by this author on: Oxford Academic PubMed Google Scholar Journal of Chromatographic Science, Volume 11, Issue 1, January 1973, Pages 4–6,...
Journal of Chromatographic Science
August 1, 1971
N. Narasimhachari, J. Spaide, Bh Heller
22 citations
The N,N-dimethyltryptamines: N,N-dimethyltryptamine (DMT), 5-methoxy-N,N-dimethyltryptamine (5-OMe-DMT) and 5-hydroxy-dimethyltryptamine (bufotenin) were completely derivatized to trimethylsilyl (TMS) derivatives with the TMS substituent on the indolic nitrogen. The GLC data of the derivatives and the MS data of combined GC-MS analysis are described. The secondary amines N-methyltryptamine...