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YAKUGAKU ZASSHI

ISSN 0031-6903

7 papers in the library · 132 citations · publishing 2008-2020

Papers

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Identification of LSD Derivatives, 1cP-LSD, MIPLA and 1B-LSD in Illegal Products as Paper Sheet

YAKUGAKU ZASSHI October 31, 2020 Rie Tanaka, Maiko Kawamura, Takashi Hakamatsuka et al. 15 citations

Lysergic acid diethylamide (LSD) is a hallucinogen, synthesized from ergot alkaloid, and controlled as a narcotic in Japan. Recently, LSD derivatives have appeared as designer drugs, all over the world. In previous study, we reported identification and analysis of four LSD derivatives in four paper sheet products. In this study, we detected three additional LSD derivatives from three paper...

Identification and Analysis of LSD Derivatives in Illegal Products as Paper Sheet

YAKUGAKU ZASSHI April 30, 2020 Rie Tanaka, Maiko Kawamura, Takashi Hakamatsuka et al. 15 citations

To prevent the abuse of new psychoactive substances (NPS), a total of 2372 substances and two plants are controlled as "Designated Substances" in Japan as of September 2019. Although the distribution of these substances has decreased for the past three years, newly-emerged NPS are still being found. In this study, we detected four lysergic acid diethylamide (LSD) derivatives as designer drugs...

Analysis of Newly Distributed Designer Drugs Detected in the Products Purchased in Fiscal Year 2008

YAKUGAKU ZASSHI February 1, 2010 Nahoko Uchiyama, Norimasa Miyazawa, Maiko Kawamura et al. 16 citations

Thirty-two psychotropic substances were listed as designated substances (Shitei-Yakubutsu, 31 compounds and 1 plant) in Japan by the Pharmaceutical Affairs Law in April 2007 for preventing the abuse of these substances. Subsequently, other psychoactive compounds were also added to this category, 40 substances (classified as 12 tryptamines, 17 phenethylamines, 3 piperazines, 6 alkyl nitrites, 1...

Simple and Rapid Screening for Psychotropic Natural Products Using Direct Analysis in Real Time (DART)-TOFMS

YAKUGAKU ZASSHI June 1, 2009 Maiko Kawamura, Yukihiro Goda, Ruri Kikura-Hanajiri 19 citations

Direct Analysis in Real Time (DART) is a novel ionization technique that provides for the rapid ionization of small molecules under ambient conditions. To investigate the trend of non-controlled psychotropic plants of abuse in Japan, a rapid screening method, without sample preparation, was developed using DART-time of flight mass spectrometer (TOFMS) for plant products. The major psychotropic...

In Vitro Screening of Psychoactive Drugs to Prevent the Abuses

YAKUGAKU ZASSHI December 1, 2008 Kanako Satoh, Ryouichi Nonaka 4 citations

The Tokyo Metropolitan Government in Japan enacted an "Ordinance concerning the abuse prevention of the psychoactive drugs" in April 2006 that prohibited the manufacture, cultivation, sales, possession, use, etc., of these drugs. Therefore, we constructed a reproducible, simple, and small-scale determination method of the psychoactive drugs for the re-uptake and the release of monoamines...

Analysis of Designer Drugs Detected in the Products Purchased in Fiscal Year 2006

YAKUGAKU ZASSHI October 1, 2008 Nahoko Uchiyama, Ruri Kikura-Hanajiri, Nobuo Kawahara et al. 46 citations

Many psychotropic substances are easily available in Japan via the Internet, thus the spread of drug abuse is becoming more serious problem. To avoid drug abuse, 32 substances have been controlled in Japan since April in 2007 by the Pharmaceutical Affairs Law as designated substances (Shitei-Yakubutsu, classified as 11 tryptamines, 11 phenethylamines, 2 piperazines, 6 alkyl nitrites, 1...

Analytical Data of Designated Substances (Shitei-Yakubutsu) Controlled by the Pharmaceutical Affairs Law in Japan, Part II: Color Test and TLC

YAKUGAKU ZASSHI June 1, 2008 Nahoko Uchiyama, Maiko Kawamura, Hiroyuki Kamakura et al. 17 citations

Many psychotropic substances are readily available in Japan via the Internet. To avoid the spread of drug abuse, some drugs have been controlled as designated substances (Shitei-Yakubutsu) in Japan since 2007 by the Pharmaceutical Affairs Law. Twenty-nine designated substances (classified as tryptamine, phenethylamine and piperazine types) were analyzed using color tests and TLC. The color...