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Cephalalgia

ISSN 0333-1024, 1468-2982

9 papers in the library · 319 citations · publishing 1999-2025

Papers

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Neurotransmitter-related functional connectivity changes in serotonin and dopamine systems after mindfulness in medication overuse headache.

Cephalalgia June 1, 2025 Davide Fedeli, Giuseppe Ciullo, Greta Demichelis et al. 7 citations

Background/HypothesisMindfulness practice has gained attention in managing chronic migraine with medication overuse headache (CM-MOH), showing clinical improvements and functional connectivity reorganization. However, the relationship between these effects and the underlying neurotransmitter systems remains unexplored.MethodsThirty-four CM-MOH patients were divided into treatment as usual (TaU,...

Philosophical aspects of migraine: Headache treatment is a human-to-human service.

Cephalalgia May 1, 2025 Mark J Emmenegger, Andreas R Gantenbein 1 citation

Migraine is a complex neurobiological disorder that extends beyond physical symptoms to encompass profound mental, emotional and existential dimensions. Despite its prevalence, the philosophical aspects of migraine remain underexplored in scientific research. This review examines migraine through a philosophical lens, addressing questions of pain, suffering, consciousness and communication. It...

DOI: 10.1177/03331024251343225 (opens in new tab) Full text (opens in new tab) Human-to-human Pain Migraines & headaches Patient-centered care +2

Increased use of illicit drugs in a Dutch cluster headache population

Cephalalgia October 5, 2018 Ilse F. de Coo, Willemijn C. Naber, Leopoldine A. Wilbrink et al. 47 citations

Introduction Many patients with cluster headache report use of illicit drugs. We systematically assessed the use of illicit drugs and their effects in a well-defined Dutch cluster headache population. Methods In this cross-sectional explorative study, 756 people with cluster headache received a questionnaire on lifetime use and perceived effects of illicit drugs. Results were compared with age...

A prospective pilot study of the effect on catecholamines of mindfulness training vs pharmacological prophylaxis in patients with chronic migraine and medication overuse headache.

Cephalalgia September 13, 2018 Licia Grazzi, Alberto Raggi, Domenico D'Amico et al.

Aim: To address whether, in patients with chronic migraine and medication overuse headache, mindfulness-based treatment is associated with changes in plasma levels of catecholamines and elusive amines that are similar to those observed in patients undergoing pharmacological prophylaxis. Methods: In this non-randomized, clinic-based effectiveness study, patients aged 18-65, with a history of...

Mindfulness-based stress reduction for treating chronic headache: A systematic review and meta-analysis

Cephalalgia June 4, 2018 Dennis Anheyer, Matthew Leach, Petra Klose et al. 80 citations

BACKGROUND: Mindfulness-based stress reduction/cognitive therapy are frequently used for pain-related conditions, but their effects on headache remain uncertain. This review aimed to assess the efficacy and safety of mindfulness-based stress reduction/cognitive therapy in reducing the symptoms of chronic headache. DATA SOURCES AND STUDY SELECTION: MEDLINE/PubMed, Scopus, CENTRAL, and PsychINFO...

Mindfulness and headache: A "new" old treatment, with new findings.

Cephalalgia October 2016 Frank Andrasik, Licia Grazzi, Domenico D'Amico et al.

Background Mindfulness refers to a host of procedures that have been practiced for centuries, but only recently have begun to be applied to varied pain conditions, with the most recent being headache. Methods We reviewed research that incorporated components of mindfulness for treating pain, with a more in depth focus on headache disorders. We also examined literature that has closely studied...

The use of illicit drugs as self-medication in the treatment of cluster headache: Results from an Italian online survey

Cephalalgia April 22, 2015 Cherubino Di Lorenzo, Gianluca Coppola, Giorgio Di Lorenzo et al. 40 citations

Background Cluster headache (CH) patients often receive unsatisfactory treatment and may explore illicit substances as alternatives. We aimed to explore this use of illicit drugs for CH treatment. Methods We invited CH patients from an Internet-based self-help group to complete a questionnaire regarding their therapeutic use of illicit substances. Results Of the 54 respondents, 29 were...

The non-hallucinogen 2-bromo-lysergic acid diethylamide as preventative treatment for cluster headache: An open, non-randomized case series

Cephalalgia March 26, 2010 Matthias Karst, John H. Halpern, Michael Bernateck et al. 104 citations

Cluster headache (CH) is a stereotyped primary headache characterized by strictly unilateral severe orbital or periorbital pain and categorized as either episodic or chronic (1,2). Its prevalence is 0.1% (3). Oxygen and sumatriptan are the treatments of choice for individual attacks, whereas verapamil, lithium, corticosteroids and other neuromodulators can suppress attacks during cluster...

Out-of-Body Experiences and Related Phenomena in Migraine Art

Cephalalgia December 1, 1999 Klaus Podoll, D Robinson 40 citations

In a collection of 562 migraine art pictures, seven pieces illustrate various elements of out-of-body experiences (OBEs) and related phenomena, including the somesthetic sensations of a duplicate or parasomatic body and the visual experiences of perceiving the own body, i.e. autoscopy, and its environment from a vantage point out of the body. Phenomenological features of the OBEs depicted are...

DOI: 10.1046/j.1468-2982.1999.1910886.x (opens in new tab) Migraine Neuropsychology Aura Cognitive psychology +2