Neurological Sciences
August 1, 2025
D Duran, P Arpaia, G D'Errico et al.
2 citations
A systematic review of electroencephalographic (EEG) correlates of Mindfulness- based treatment for chronic pain is presented. Recent technological advances have made EEG acquisition more accessible and also reliable. EEG monitoring before, during, and after treatment might support efficacy assessment and enable real- time adaptive intervention. The preliminary research extracted 131 papers...
Cephalalgia
June 1, 2025
Davide Fedeli, Giuseppe Ciullo, Greta Demichelis et al.
7 citations
Background/HypothesisMindfulness practice has gained attention in managing chronic migraine with medication overuse headache (CM-MOH), showing clinical improvements and functional connectivity reorganization. However, the relationship between these effects and the underlying neurotransmitter systems remains unexplored.MethodsThirty-four CM-MOH patients were divided into treatment as usual (TaU,...
The Journal of Headache and Pain
June 11, 2024
Davide Fedeli, Giuseppe Ciullo, Greta Demichelis et al.
17 citations
Mindfulness practice has gained interest in the management of Chronic Migraine associated with Medication Overuse Headache (CM-MOH). Mindfulness is characterized by present-moment self-awareness and relies on attention control and emotion regulation, improving headache-related pain management. Mindfulness modulates the Default Mode Network (DMN), Salience Network (SN), and Fronto-Parietal...
The Journal of Headache and Pain
July 14, 2023
Licia Grazzi, Domenico D'Amico, Erika Guastafierro et al.
Mindfulness gained considerable attention for migraine management, but RCTs are lacking. We aimed to assess the efficacy of a six-sessions mindfulness-based treatment added to treatment as usual (TaU) in patients with Chronic Migraine (CM) and Medication Overuse Headache (MOH) on headache frequency, medication intake, quality of life, disability, depression and anxiety, cutaneous allodynia,...
Neurological Sciences
September 2022
Licia Grazzi
Mindfulness and other behavioral approaches have demonstrated efficacy in treatment of different kinds of chronic pain condition and migraine in particular. Such treatments are of particular utility in the treatment of chronic forms of migraine, also associated to medication overuse headache, in reason of the relevant comorbidity - and bidirectional relationship - between migraine, and two of...
Cephalalgia
September 13, 2018
Licia Grazzi, Alberto Raggi, Domenico D'Amico et al.
Aim: To address whether, in patients with chronic migraine and medication overuse headache, mindfulness-based treatment is associated with changes in plasma levels of catecholamines and elusive amines that are similar to those observed in patients undergoing pharmacological prophylaxis. Methods: In this non-randomized, clinic-based effectiveness study, patients aged 18-65, with a history of...
The Journal of Headache and Pain
December 2017
Licia Grazzi, Emanuela Sansone, Alberto Raggi et al.
Chronic Migraine (CM) is a disabling condition, worsened when associated with Medication Overuse (MO). Mindfulness is an emerging technique, effective in different pain conditions, but it has yet to be explored for CM-MO. We report the results of a study assessing a one-year course of patients' status, with the hypothesis that the effectiveness of a mindfulness-based approach would be similar...
Neurological Sciences
May 2017
Licia Grazzi, Domenico D'Amico, Alberto Raggi et al.
Chronic migraine (CM) is a disabling condition arising from a complex mixture of interconnected biological, psychological and social factors, and is often associated with medication overuse (MO). Mindfulness is emerging as a helpful treatment for pain, and one study showed that the longitudinal 12 months' course of CM-MO patients that attended mindfulness-based treatment alone was similar to...
Cephalalgia
October 2016
Frank Andrasik, Licia Grazzi, Domenico D'Amico et al.
Background Mindfulness refers to a host of procedures that have been practiced for centuries, but only recently have begun to be applied to varied pain conditions, with the most recent being headache. Methods We reviewed research that incorporated components of mindfulness for treating pain, with a more in depth focus on headache disorders. We also examined literature that has closely studied...