To use or not to use: an update on licit and illicit ketamine use
Substance Abuse and Rehabilitation March 1, 2011 Jih-Heng Li, Vickna Kasinather, Cheung et al. 146 citations
Ketamine, a derivative of phencyclidine that was developed in the 1960s, is an anesthetic and analgesic with hallucinogenic effects. In this paper, the pharmacological and toxicological effects of ketamine are briefly reviewed. Ketamine possesses a wide safety margin but such a therapeutic benefit is somewhat offset by its emergence phenomenon (mind-body dissociation and delirium) and...