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Molecular Biology Reports

ISSN 1573-4978

2 papers in the library · publishing 2020-2025

Papers

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Effects of cerebrolysin on behavioral changes and the tryptophan-kynurenine pathway in the prefrontal cortex of male mice in the ketamine model of schizophrenia.

Molecular Biology Reports July 16, 2025 Vida Mafikandi, Leila Hosseini, Fatemehsadat Seyedaghamiri et al.

Cerebrolysin (CBL), a peptide derived from pig brain, is recognized for its neuroprotective and anti-inflammatory properties. This research aimed to investigate the effects of CBL on anxiety- and depression-like behaviors, spatial memory, the tryptophan/kynurenine (TRP/KYN) pathway, and inflammation in the prefrontal cortex (PFC) of a mouse model for schizophrenia. Thirty-six male BALB/c mice...

Psychedelics as an emerging novel intervention in the treatment of substance use disorder: a review

Molecular Biology Reports December 1, 2020 Alec J. DiVito, Robert F. Leger

Classical psychedelics are a group of drugs characterized by their activation of the serotonin-2A (5-hydroxytryptamine-2A; 5-HT2A) receptor and the unique hallucinogenic and mystical-type experiences that result. After a substantial period of restrictions limiting investigations into the therapeutic potential of psychedelics, a relatively recent recommencement of interest has sparked the...