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Robert F. Leger

2 papers in the library · 54 citations · publishing 2020-2021

Papers

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Assessing the effects of methodological differences on outcomes in the use of psychedelics in the treatment of anxiety and depressive disorders: A systematic review and meta-analysis

Journal of Psychopharmacology September 14, 2021 Robert F. Leger, Ellen M. Unterwald 54 citations

Background: Classical psychedelics are a group of drugs which act as agonists on the serotonin-2A (5-HT2A) receptor. Evidence suggests they may have a uniquely rapid and enduring positive effect on mood. However, marked heterogeneity between methodological designs in this emerging field remains a significant concern. Aims: To determine how differences in the type of psychedelic agent used and...

Psychedelics as an emerging novel intervention in the treatment of substance use disorder: a review

Molecular Biology Reports December 1, 2020 Alec J. DiVito, Robert F. Leger

Classical psychedelics are a group of drugs characterized by their activation of the serotonin-2A (5-hydroxytryptamine-2A; 5-HT2A) receptor and the unique hallucinogenic and mystical-type experiences that result. After a substantial period of restrictions limiting investigations into the therapeutic potential of psychedelics, a relatively recent recommencement of interest has sparked the...