Scientific Reports
October 28, 2025
Sacha Haudry, Natacha Lambert, Christian Gaser et al.
Meditation is thought to promote healthy aging by improving mental health, preserving brain integrity and reducing Alzheimer's disease risk. We examined the impact of long-term meditation expertise and an 18-month meditation training on brain aging in older adults using machine learning. We included 25 Older Expert Meditators (OldExpMed) with > 20 years of practice and 135 Cognitively...
Scientific Reports
May 15, 2025
Florence Requier, Hamed Mohammadi, Harriet Demnitz-King et al.
With aging, slight changes in some cognitive processes can be observed. Therefore, we aimed to assess if meditation expertise is associated with preserved cognition in key domains affected in aging. We used data from two older-adult samples of the Medit-Ageing Age-well Study: 135 non-meditators and 27 expert meditators. We examined group differences in four objective cognitive domains...
Imaging Neuroscience
2025
Sacha Haudry, Sophie Dautricourt, Julie Gonneaud et al.
Meditation training in older adults has been proposed as a non-pharmacological intervention to promote healthy aging and lower the risks of developing Alzheimer's disease (AD). Resting-state dynamic functional network connectivity (dFNC) highlighted two brain states, the "strongly connected" and "default mode network (DMN)-negatively connected" states, associated with protective factors for...
Sci Rep
November 27, 2024
Sacha Haudry, Anne-Laure Turpin, Brigitte Landeau et al.
3 citations
Decoding meditation mechanisms underlying brain preservation and psycho-affective health in older expert meditators and older meditation-naive participants.
Sci Rep
November 27, 2024
Sacha Haudry, Anne-Laure Turpin, Brigitte Landeau et al.
3 citations
Decoding meditation mechanisms underlying brain preservation and psycho-affective health in older expert meditators and older meditation-naive participants.
Scientific Reports
November 2, 2024
Marco Schlosser, Julie Gonneaud, Stefano Poletti et al.
2 citations
Understanding the factors that predict why some individuals perceive to respond more to meditation training than others could impact the development, efficacy, adherence levels, and implementation of meditation-based interventions. We investigated individual-level variables associated with self- and teacher-perceived responsiveness to longer-term meditation training. This study presents a...
JAMA Neurology
October 10, 2022
Gaël Chételat, Antoine Lutz, Olga Klimecki et al.
45 citations
Importance: No lifestyle-based randomized clinical trial directly targets psychoaffective risk factors of dementia. Meditation practices recently emerged as a promising mental training exercise to foster brain health and reduce dementia risk. Objective: To investigate the effects of meditation training on brain integrity in older adults. Design, Setting, and Participants: Age-Well was a...
Scientific Reports
August 25, 2017
Gaël Chételat, Florence Mezenge, Clémence Tomadesso et al.
67 citations
Aging is associated with progressive cerebral volume and glucose metabolism decreases. Conditions such as stress and sleep difficulties exacerbate these changes and are risk factors for Alzheimer's disease. Meditation practice, aiming towards stress reduction and emotion regulation, can downregulate these adverse factors. In this pilot study, we explored the possibility that lifelong meditation...