medRxiv
October 2, 2026
Pierre Champetier, Anaïs Hamel, Stéphane Rehel et al.
preprint
Abstract Study objectives Aging is associated with increased sleep complaints and changes in sleep architecture, microstructure and rest-activity rhythms. Meditation-based interventions have shown benefits on subjective sleep quality, but their effects on objective sleep parameters remain largely underexplored. This study investigated the effects of an 18-month meditation intervention on sleep...
Scientific Reports
May 15, 2025
Florence Requier, Hamed Mohammadi, Harriet Demnitz-King et al.
With aging, slight changes in some cognitive processes can be observed. Therefore, we aimed to assess if meditation expertise is associated with preserved cognition in key domains affected in aging. We used data from two older-adult samples of the Medit-Ageing Age-well Study: 135 non-meditators and 27 expert meditators. We examined group differences in four objective cognitive domains...
Neuropsychology, development, and cognition. Section B, Aging, neuropsychology and cognition
March 1, 2025
Florence Requier, Harriet Demnitz-King, Eric Frison et al.
Aging is associated with cognitive changes, even in the absence of brain pathology. This study aimed to determine if meditation training, by comparison to active and passive control groups, is linked to changes in the perception of cognitive functioning in older adults. One hundred thirty-four healthy older participants from the Age-Well Randomized Clinical Trial were included: 45 followed a...
Scientific Reports
November 27, 2024
Sacha Haudry, Anne-Laure Turpin, Brigitte Landeau et al.
3 citations
Meditation is a mental training approach that can improve mental health and well-being in aging. Yet the underlying mechanisms remain unknown. The Medit-Ageing model stipulates that three mechanisms - attentional, constructive, and deconstructive - upregulate positive psycho-affective factors and downregulate negative ones. To test this hypothesis, we measured brain structural MRI and...
Scientific Reports
November 27, 2024
Sacha Haudry, Anne-Laure Turpin, Brigitte Landeau et al.
3 citations
Meditation is a mental training approach that can improve mental health and well-being in aging. Yet the underlying mechanisms remain unknown. The Medit-Ageing model stipulates that three mechanisms - attentional, constructive, and deconstructive - upregulate positive psycho-affective factors and downregulate negative ones. To test this hypothesis, we measured brain structural MRI and...
Scientific Reports
November 2, 2024
Marco Schlosser, Julie Gonneaud, Stefano Poletti et al.
2 citations
Understanding the factors that predict why some individuals perceive to respond more to meditation training than others could impact the development, efficacy, adherence levels, and implementation of meditation-based interventions. We investigated individual-level variables associated with self- and teacher-perceived responsiveness to longer-term meditation training. This study presents a...
JAMA Network Open
July 3, 2023
Harriet Demnitz-King, Florence Requier, Tim Whitfield et al.
Nonpharmacological interventions are a potential strategy to maintain or promote cognitive functioning in older adults. To investigate the effects of 18 months' meditation training and 18 months' non-native language training on cognition in older adults. This study was a secondary analysis of the Age-Well trial, an 18-month, observer-masked, randomized clinical trial with 3 parallel arms....
JAMA Neurology
October 10, 2022
Gaël Chételat, Antoine Lutz, Olga Klimecki et al.
45 citations
Importance: No lifestyle-based randomized clinical trial directly targets psychoaffective risk factors of dementia. Meditation practices recently emerged as a promising mental training exercise to foster brain health and reduce dementia risk. Objective: To investigate the effects of meditation training on brain integrity in older adults. Design, Setting, and Participants: Age-Well was a...
Alzheimer's Research & Therapy
September 6, 2022
Tim Whitfield, Harriet Demnitz-King, Marco Schlosser et al.
Older individuals with subjective cognitive decline (SCD) perceive that their cognition has declined but do not show objective impairment on neuropsychological tests. Individuals with SCD are at elevated risk of objective cognitive decline and incident dementia. Non-pharmacological interventions (including mindfulness-based and health self-management approaches) are a potential strategy to...