Plasma inflammatory cytokines and treatment-resistant depression with comorbid pain: improvement by ketamine
Journal of Neuroinflammation September 15, 2021 Yanling Zhou, Chengyu Wang, Xiaofeng Lan et al. 61 citations
Treatment-resistant depression (TRD) and pain frequently coexist clinically. Ketamine has analgesic and antidepressant effects, but few studies have evaluated individual differences in antidepressant outcomes to repeated ketamine in TRD patients with comorbid pain. Our aims were to determine the difference in ketamine’s antidepressant effects in TRD patients with or without pain and then to...