Dreams are sources of inspiration for artists tapping into their subconscious states, but the uncertainty of fragmented elements and difficulty of recall make it challenging to harness dream-based inspiration for creative work. Generative AI shares a similar ambiguity with dreams, producing unexpected outputs that offer reinterpretation in the creative process. It suggests GenAI may help engage...
Despite the clinical benefits of ketamine in treating major depressive disorder (MDD), some patients exhibit drug resistance, and the intricate mechanisms underlying this await comprehensive explication. We used metabolomics to find biomarkers for ketamine efficacy and uncover its mechanisms of action. The study included 40 MDD patients treated with ketamine in the discovery cohort and 24...
Amygdala subregion-based network dysfunction has been determined to be centrally implicated in major depressive disorder (MDD). Little is known about whether ketamine modulates amygdala subarea-related networks. We aimed to investigate the relationships between changes in the resting-state functional connectivity (RSFC) of amygdala subregions and ketamine treatment and to identify important...