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P. Llorca

5 papers in the library · 172 citations · publishing 2021-2024

Papers

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Cannabis use and cognitive biases in people with first-episode psychosis and their siblings

Psychological Medicine November 1, 2024 L. Roldán, Teresa Sánchez‐Gutiérrez, I. Fernández-Arias et al.

Background Cannabis use and familial vulnerability to psychosis have been associated with social cognition deficits. This study examined the potential relationship between cannabis use and cognitive biases underlying social cognition and functioning in patients with first episode psychosis (FEP), their siblings, and controls. Methods We analyzed a sample of 543 participants with FEP, 203...

The contribution of cannabis use to the increased psychosis risk among minority ethnic groups in Europe.

Psychological Medicine May 9, 2024 J. Selten, Marta Di Forti, Diego Quattrone et al.

BACKGROUND We examined whether cannabis use contributes to the increased risk of psychotic disorder for non-western minorities in Europe. METHODS We used data from the EU-GEI study (collected at sites in Spain, Italy, France, the United Kingdom, and the Netherlands) on 825 first-episode patients and 1026 controls. We estimated the odds ratio (OR) of psychotic disorder for several groups of...

Cannabis use as a potential mediator between childhood adversity and first-episode psychosis: results from the EU-GEI case–control study

Psychological Medicine May 4, 2023 Giulia Trotta, Victoria Rodriguez, Diego Quattrone et al.

Abstract Background Childhood adversity and cannabis use are considered independent risk factors for psychosis, but whether different patterns of cannabis use may be acting as mediator between adversity and psychotic disorders has not yet been explored. The aim of this study is to examine whether cannabis use mediates the relationship between childhood adversity and psychosis. Methods Data were...

Ketamine for the acute treatment of severe suicidal ideation: double blind, randomised placebo controlled trial

British medical journal February 2, 2022 M. Abbar, C. Demattei, Wissam El-Hage et al. 172 citations

Abstract Objective To confirm the rapid onset anti-suicidal benefits of ketamine in the short term and at six weeks, overall and according to diagnostic group. Design Prospective, double blind, superiority, randomised placebo controlled trial. Setting Seven French teaching hospitals between 13 April 2015 and 12 March 2019. Eligibility criteria for participants Aged 18 or older with current...

The continuity of effect of schizophrenia polygenic risk score and patterns of cannabis use on transdiagnostic symptom dimensions at first-episode psychosis: findings from the EU-GEI study

Translational Psychiatry August 10, 2021 Diego Quattrone, Ulrich Reininghaus, Anne Richards et al.

Diagnostic categories do not completely reflect the heterogeneous expression of psychosis. Using data from the EU-GEI study, we evaluated the impact of schizophrenia polygenic risk score (SZ-PRS) and patterns of cannabis use on the transdiagnostic expression of psychosis. We analysed first-episode psychosis patients (FEP) and controls, generating transdiagnostic dimensions of psychotic symptoms...