The content of consciousness (cC) constitutes an essential part of human life and is at the very heart of the hard problem of consciousness. The cC of a person (e.g., study participant) has been examined indirectly by evaluating the person’s behavioral reports, bodily signs, or neural signals. However, the measures do not reflect the full spectrum of the person’s cC. In this paper, we define a...
Journal of NeuroscienceOctober 5, 2011Daisuke H. Tanaka, Kazuya Toriumi, Ken-ichiro Kubo et al.
Phencyclidine (PCP) is a noncompetitive NMDA receptor antagonist, and it induces schizophreniform cognitive deficits in healthy humans and similar cognitive deficits in rodents. Although the PCP-induced cognitive deficits appear to be accompanied and possibly caused by dysfunction of GABAergic inhibitory interneurons in the prefrontal cortex (PFC), the potential benefit(s) of GABAergic...