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Chelsea M Kaplan

5 papers in the library · 1 citation · publishing 2025-2026

Papers

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Subanesthetic nitrous oxide alters large-scale network organization and insula connectivity during visual stimulation

Communications Biology August 31, 2026 Niloufar Pouyan, Chelsea Kaplan, Tony E. Larkin et al.

Pharmacological agents that alter consciousness, including classic psychedelics and non-classic agents such as nitrous oxide, are known to affect multiple domains of conscious experience, including visual perception. While most neuroimaging studies rely on resting-state data to characterize altered states of consciousness, task-based approaches enable investigation of specific perceptual...

JAK-STAT pathway inhibition modulates centrally sensitised default mode network hubs in rheumatoid arthritis pain

medRxiv July 14, 2026 Kristian Stefanov, Joel T. Parkinson, Flavia Sunzini et al.

Abstract Nociplastic pain represents a major burden across immune-mediated inflammatory diseases (IMIDs). It is hypothesised, but not yet demonstrated, that peripheral inflammation promotes nociplastic pain by bottom-up sensitisation of the central nervous system (CNS). In rheumatoid arthritis (RA), a prototypic IMID, we used ultra–high field (7T) brain resting-state functional MRI to evaluate...

Acute effects of nitrous oxide on visual processing: a connectome study in healthy adults.

Research Square January 12, 2026 Niloufar Pouyan, Chelsea M Kaplan, Tony E. Larkin et al.

Nitrous oxide (N2O) produces perceptual alterations and changes in large-scale brain network organization, yet its effects on task-specific visual processing remain unclear. Given the prominence of visual alterations during psychedelic exposure, we investigated how subanesthetic N2O modulates functional connectivity during visual stimulation. Thirteen healthy adults completed a...

Pictorial representation of illness and self measure (PRISM): A putative transdiagnostic tool for evaluating therapeutic effects of psychedelic treatments.

Journal of psychopharmacology (Oxford, England) May 1, 2025 Niloufar Pouyan, Jacob S. Aday, Steven E. Harte et al. 1 citation

Patients with refractory conditions often identify themselves with their illness, which affects multiple aspects of their lives. The pictorial representation of illness and self measure (PRISM) is a tool used to assess the enmeshment of individuals' perception of self with a particular medical condition, broadly termed self-condition enmeshment. This study aimed to evaluate changes in PRISM...

Pictorial representation of illness and self measure (PRISM): A putative transdiagnostic tool for evaluating therapeutic effects of psychedelic treatments

Universität Zürich, ZORA May 1, 2025 Niloufar Pouyan, Jacob S. Aday, Steven E. Harte et al.

Background: Patients with refractory conditions often identify themselves with their illness, which affects multiple aspects of their lives. The pictorial representation of illness and self measure (PRISM) is a tool used to assess the enmeshment of individuals' perception of self with a particular medical condition, broadly termed self-condition enmeshment. Aims: This study aimed to evaluate...