Regulation of REM and NREM Sleep by Preoptic Glutamatergic Neurons.
Sleep May 26, 2025 Alejandra Mondino, Amir Jadidian, Brandon A Toth et al. 4 citations
The preoptic area of the hypothalamus is key for the control of sleep onset and sleep homeostasis. Although traditionally considered exclusively somnogenic, recent studies identified a group of preoptic glutamatergic neurons that promote wakefulness. Specifically, our previous investigations demonstrated that chemogenetic stimulation of glutamatergic neurons within the medial-lateral preoptic...
DOI: 10.1093/sleep/zsaf141 (opens in new tab)
Full text (opens in new tab)
Activating systems
Dreadd
Brief arousals
Consciousness
+6