Ana Margarida Araújo

2 papers in the library · 290 citations · publishing 2015-2018

Papers

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GC-MS metabolomics reveals disturbed metabolic pathways in primary mouse hepatocytes exposed to subtoxic levels of 3,4-methylenedioxymethamphetamine (MDMA).

Archives of Toxicology November 2018 Ana Margarida Araújo, Maria de Lourdes Bastos, Eduarda Fernandes et al.

3,4-Methylenedioxymethamphetamine (MDMA, ecstasy) is a well-known hepatotoxic drug. Although its toxicity has been thoroughly studied at high concentrations, there is still insufficient knowledge on possible alterations of cell function at subtoxic concentrations, which are in fact more representative concentrations of intoxication scenarios. In this study, a gas chromatography-mass...

DOI: 10.1007/s00204-018-2314-9 Full text MDMA Hepatotoxicity Metabolomics Primary mouse hepatocytes +1

The hallucinogenic world of tryptamines: an updated review.

Archives of Toxicology August 1, 2015 Ana Margarida Araújo, Félix Carvalho, Maria de Lourdes Bastos et al. 290 citations

In the area of psychotropic drugs, tryptamines are known to be a broad class of classical or serotonergic hallucinogens. These drugs are capable of producing profound changes in sensory perception, mood and thought in humans and act primarily as agonists of the 5-HT2A receptor. Well-known tryptamines such as psilocybin contained in Aztec sacred mushrooms and N,N-dimethyltryptamine (DMT),...

DOI: 10.1007/s00204-015-1513-x Full text