JAMA Psychiatry
October 21, 2026
Ellen Bradley, Parker Kelley, Balázs Szigeti et al.
This nonrandomized clinical trial assesses associations between psilocybin therapy and changes in systemic markers of inflammation and mitochondrial stress in people with Parkinson disease and mood dysfunction.
SSRN Electronic Journal
2026
Dennis Parker Kelley, Gabriel Sturm, Katy Venable et al.
preprint
Serotonergic psychedelics produce therapeutic effects in clinical trials of diverse neuropsychiatric disorders, and preclinical models of inflammatory, cardiometabolic, and neuropsychiatric diseases. These effects appear largely mediated by the serotonin 5-HT2A receptor (5-HT2AR). How could psychedelics elicit transdiagnostic therapeutic effects through a single receptor across tissues as...
Psychological Review
December 25, 2023
Alexandra D Crosswell, Stefanie E Mayer, Lauren N Whitehurst et al.
Engaging in contemplative practice like meditation, yoga, and prayer, is beneficial for psychological and physical well-being. Recent research has identified several underlying psychological and biological pathways that explain these benefits. However, there is not yet consensus on the underlying overlapping physiological mechanisms of contemplative practice benefits. In this article, we...
PsyArXiv
December 20, 2022
Alexandra D Crosswell, Stefanie Eva Mayer, Lauren N Whitehurst et al.
preprint
Engaging in contemplative practices like meditation, yoga, and prayer, is greatly beneficial for psychological and physical well-being. Recent research has identified some of the underlying psychological and biological pathways that explain these benefits. However, an overarching model has yet to be developed that incorporates the latest research from intervention and experimental studies with...