Human brain changes after first psilocybin use.
Nature Communications May 5, 2026 T Lyons, M Spriggs, L Kerkelä et al. 19 citations
Psychedelics have robust effects on acute brain function and long-term behavior but whether they also cause enduring functional and anatomical brain changes is largely unknown. In an exploratory, placebo-controlled, within-subjects, electroencephalography (EEG), and magnetic resonance imaging (MRI) study in 28 healthy, entirely psychedelic-naive participants, anatomical and functional brain...