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Felipe Augusto Cini da Silva

1 paper in the library · 9 citations · publishing 2019

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d-Lysergic acid diethylamide has major potential as a cognitive enhancer

bioRxiv (Cold Spring Harbor Laboratory) December 6, 2019 Felipe Augusto Cini da Silva, Isis M. Ornelas, Encarni Marcos et al. 9 citations preprint

Abstract Psychedelic agonists of serotonin receptors induce neural plasticity and synaptogenesis, but their potential to enhance learning remains uncharted. Here we show that a single dose of d-LSD, a potent serotonergic agonist, increased novel object preference in young and adult rats several days after treatment. d-LSD alone did not increase preference in old animals, but could rescue it to...