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Hélène Richard-Lepouriel

5 papers in the library · 48 citations · publishing 2024-2026

Papers

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[Intravenous ketamine in suicidal crisis : indications and patient referral].

Revue Médicale Suisse September 16, 2026 Rayan Nasserdine, Laura Xhymshiti, Anne-Charlotte Paporé et al.

Intravenous (IV) ketamine is a rapidly acting therapeutic option for the management of treatment-resistant depression and acute suicidal crisis. Unlike conventional antidepressants, its effects may occur within hours, allowing a rapid reduction in suicidal ideation and psychological distress. Its use remains specialized and requires hospital-based care with medical monitoring and a...

Psychedelic-induced hypomania and mania: a systematic review and meta-analysis.

Molecular Psychiatry May 29, 2026 Mickael Eskinazi, Rayan Nasserdine, Romane M Cusin et al.

Serotonergic psychedelics are increasingly investigated as treatments for affective disorders. Concerns persist regarding their potential to induce hypomania or mania, particularly in individuals with bipolar spectrum vulnerability. Whether these substances precipitate transient mood switches or contribute to persistent bipolar illness or diagnostic transition remains unclear. We conducted a...

Reconsidering evidence for psychedelic-induced psychosis: an overview of reviews, a systematic review, and meta-analysis of human studies.

Molecular Psychiatry March 1, 2025 Michel Sabé, Adi Sulstarova, Alban Glangetas et al. 39 citations

Persons with schizophrenia are excluded from psychedelic-assisted therapy due to concerns about the risk of triggering or worsening psychosis. However, there is limited meta-analytic data on the risk of psychedelic-induced psychosis in individuals with pre-existing psychotic disorders. We conducted a systematic review, meta-analysis, and overview of reviews to assess the incidence of...

DOI: 10.1038/s41380-024-02800-5 (opens in new tab) Full text (opens in new tab) Schizophrenia Psychedelics Mental health Drug safety +1

Case Report: Intranasal esketamine combined with a form of generative artificial intelligence in the management of treatment-resistant depression.

Frontiers in Psychiatry 2025 Alexandre Fraichot, Sophie Favre, Hélène Richard-Lepouriel 1 citation

Intranasal Esketamine is an effective rapid-acting antidepressant currently used to treat treatment-resistant depression. Artificial intelligence is another emerging tool in medicine, but little is known about the effectiveness of combining these innovations in psychiatry. This case report presents the outcome of a 37-year-old patient who received intranasal Esketamine treatment (84 mg) and...

Psychothérapie assistée par psychédéliques (PAP) : le modèle genevois

Annales Médico-psychologiques revue psychiatrique July 10, 2024 Federico Seragnoli, Gabriel Thorens, Louise Penzenstadler et al. 8 citations

Dans cet article, nous avons pour objectif de décrire un modèle interdisciplinaire de psychothérapie assistée par psychédéliques (PAP) que nous avons développé dans un cadre institutionnel aux hôpitaux universitaires de Genève. La psychothérapie assistée par psychédéliques (PAP) est une approche psychothérapeutique exploitant l’altération de l’état de conscience induite par une substance...