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Jean-François Briefer

3 papers in the library · 8 citations · publishing 2024-2026

Papers

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Psychedelic-induced hypomania and mania: a systematic review and meta-analysis.

Molecular Psychiatry May 29, 2026 Mickael Eskinazi, Rayan Nasserdine, Romane M Cusin et al.

Serotonergic psychedelics are increasingly investigated as treatments for affective disorders. Concerns persist regarding their potential to induce hypomania or mania, particularly in individuals with bipolar spectrum vulnerability. Whether these substances precipitate transient mood switches or contribute to persistent bipolar illness or diagnostic transition remains unclear. We conducted a...

Limited prognostic value of early maladaptive schemas for acute psychedelic experience and symptom improvement

Research Square December 1, 2025 Albert Buchard, Federico Seragnoli, Michel Sabé et al.

Abstract Early maladaptive schemas (EMS) are highly prevalent in patients seeking psychedelic-assisted psychotherapy and correlate strongly with baseline depression and anxiety. This study characterized EMS in 192 adults and longitudinally followed 74 patients receiving psilocybin- or LSD-assisted therapy. We found that baseline schema burden, particularly related to failure and defectiveness,...

Psychothérapie assistée par psychédéliques (PAP) : le modèle genevois

Annales Médico-psychologiques revue psychiatrique July 10, 2024 Federico Seragnoli, Gabriel Thorens, Louise Penzenstadler et al. 8 citations

Dans cet article, nous avons pour objectif de décrire un modèle interdisciplinaire de psychothérapie assistée par psychédéliques (PAP) que nous avons développé dans un cadre institutionnel aux hôpitaux universitaires de Genève. La psychothérapie assistée par psychédéliques (PAP) est une approche psychothérapeutique exploitant l’altération de l’état de conscience induite par une substance...