Relationships between Beta-Amyloid and Functional Connectivity in Different Components of the Default Mode Network in Aging
Cerebral Cortex March 7, 2011 Elizabeth C. Mormino, Andre Smiljic, Amynta O. Hayenga et al. 349 citations
Although beta-amyloid (Aβ) deposition is a characteristic feature of Alzheimer's disease (AD), this pathology is commonly found in elderly normal controls (NC). The pattern of Aβ deposition as detected with Pittsburgh compound-B positron emission tomography (PIB-PET) imaging shows substantial spatial overlap with the default mode network (DMN), a group of brain regions that typically...