Ya-Zhu Xu

Synthesis of deuterium labeled standards of 5‐methoxy‐N,N‐dimethyltryptamine (5‐Meo‐DMT)

Journal of Labelled Compounds and Radiopharmaceuticals August 14, 2006 Ya-Zhu Xu, Chinpiao Chen 14 citations

Abstract The Batcho‐Leimgruber strategy was employed to synthesize 5‐[ 2 H 3 ]‐methoxy‐1 H ‐indole 4 from commercially available 5‐hydroxy‐2‐nitrotoluene 1 and CD 3 I. Compound 4 was treated with oxalyl chloride, dimethylamine and lithium aluminum hydride to yield 5‐[ 2 H 3 ]‐methoxy‐ N , N ‐dimethyltryptamine 6 . Copyright © 2006 John Wiley & Sons, Ltd.