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AI-extracted from the abstract
| Characteristics |
Synthesis paper
Peer reviewed
|
| Topics |
5-MeO-DMT
DMT
|
| Keywords |
Dimethylamine
Oxalyl chloride
Yield engineering
Lithium medication
Indole test
Aluminum hydride
Medicinal chemistry
Combinatorial chemistry
Organic chemistry
Methanol
|
| Citations |
14 |
| Key points |
5-[2H3]-methoxy-N,N-dimethyltryptamine was synthesized from 5-hydroxy-2-nitrotoluene and CD3I via the Batcho-Leimgruber strategy. |
Abstract
Abstract The Batcho‐Leimgruber strategy was employed to synthesize 5‐[ 2 H 3 ]‐methoxy‐1 H ‐indole 4 from commercially available 5‐hydroxy‐2‐nitrotoluene 1 and CD 3 I. Compound 4 was treated with oxalyl chloride, dimethylamine and lithium aluminum hydride to yield 5‐[ 2 H 3 ]‐methoxy‐ N , N ‐dimethyltryptamine 6 . Copyright © 2006 John Wiley & Sons, Ltd.
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1993