Synthesis of deuterium labeled standards of 5‐methoxy‐N,N‐dimethyltryptamine (5‐Meo‐DMT)
Journal of Labelled Compounds and Radiopharmaceuticals August 14, 2006 DOI: 10.1002/jlcr.1109 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Synthesis paper Peer reviewed |
|---|---|
| Topics | 5-MeO-DMT DMT |
| Keywords | Dimethylamine Oxalyl chloride Yield engineering Lithium medication Indole test Aluminum hydride Medicinal chemistry Combinatorial chemistry Organic chemistry Methanol |
| Citations | 14 |
| Key points | 5-[2H3]-methoxy-N,N-dimethyltryptamine was synthesized from 5-hydroxy-2-nitrotoluene and CD3I via the Batcho-Leimgruber strategy. |
Abstract
Abstract The Batcho‐Leimgruber strategy was employed to synthesize 5‐[ 2 H 3 ]‐methoxy‐1 H ‐indole 4 from commercially available 5‐hydroxy‐2‐nitrotoluene 1 and CD 3 I. Compound 4 was treated with oxalyl chloride, dimethylamine and lithium aluminum hydride to yield 5‐[ 2 H 3 ]‐methoxy‐ N , N ‐dimethyltryptamine 6 . Copyright © 2006 John Wiley & Sons, Ltd.
Citations in the library
Cited by 3
- Microwave‐accelerated preparation and analytical characterization of 5‐ethoxy‐N,N‐dialkyl‐[α,α,β,β‐H4]‐ and [α,α,β,β‐D4]‐tryptamines Drug Testing and Analysis December 29, 2010
- Synthesis of deuterium‐labelled standards of (±)‐DOM and (±)‐MMDA Journal of Labelled Compounds and Radiopharmaceuticals June 1, 2007
- Synthesis of a deuterium‐labelled standard of bufotenine (5‐HO‐DMT) Journal of Labelled Compounds and Radiopharmaceuticals October 1, 2007