3,4-Methylenedioxymethamphetamine facilitates fear extinction learning
Translational Psychiatry September 15, 2015 Matthew B Young, Raül Andero, Kerry J. Ressler et al. 137 citations
Abstract Acutely administered 3,4-methylenedioxymethamphetamine (MDMA, ‘ecstasy’) has been proposed to have long-term positive effects on post-traumatic stress disorder (PTSD) symptoms when combined with psychotherapy. No preclinical data support a mechanistic basis for these claims. Given the persistent nature of psychotherapeutic gains facilitated by MDMA, we hypothesized that MDMA improves...