Concomitant THC and stress adolescent exposure induces impaired fear extinction and related neurobiological changes in adulthood.
Neuropharmacology January 2019 Rocio Saravia, Marc Ten-Blanco, Marina Julià-Hernández et al.
Δ9-tetrahydrocannabinol (THC) consumption during adolescence is reported to be a risk factor for the appearance of psychiatric disorders later in life. The interaction between genetic or environmental events and cannabinoid exposure in the adolescent period can also contribute to exacerbate behavioural deficits in adulthood. Here we investigate the effects of THC treatment as well as the...
DOI: 10.1016/j.neuropharm.2018.11.016 (opens in new tab)
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Adolescence
Amygdala
Dendritic spines
Fear extinction
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