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Aaron Keshen

6 papers in the library · 16 citations · publishing 2024-2026

Papers

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Psilocybin as a Transdiagnostic Treatment for Eating Disorders and Comorbid Psychopathology: Implications for Clinical Nosology and Research Directions

International Journal of Eating Disorders July 2, 2026 Elena Koning, Jérémie Richard, Aaron Keshen

OBJECTIVE: Eating disorders (EDs) are characterized by high rates of psychiatric comorbidity and suboptimal treatment outcomes. There remain critical gaps in research, including the exploration of effective transdiagnostic interventions. This forum article examines the potential of psilocybin treatment (PT) as a transdiagnostic intervention for EDs and common comorbidities, including the...

Psilocybin Treatment as an Adjunct to Cognitive Behavioral Therapy for Eating Disorders: Therapeutic Rationale & Considerations for Protocol Development.

Behavioral sciences (Basel, Switzerland) March 6, 2026 Elena Koning, Susan Gamberg, Aaron Keshen 1 citation

Eating disorders (EDs) remain challenging to treat, with high dropout and low remission rates in cognitive-behavioral therapy for EDs (CBT-ED). Psilocybin treatment (PT) demonstrates therapeutic potential to enhance CBT-ED by exerting several neurobiological, psychological, and experiential effects (e.g., antidepressant, neuroplasticity, emotional openness) that are hypothesized to increase...

Innovative Pharmacological Approaches to Eating Disorder Treatment.

The Psychiatric clinics of North America March 1, 2026 Aaron Keshen, Stephen Touyz, Emilie Lacroix et al.

This article explores innovative pharmacologic treatments for eating disorders, focusing on psychedelics, stimulant medications, and other emerging therapies. Preliminary evidence for psychedelics (eg, psilocybin) highlight their potential to enhance cognitive flexibility and support psychological interventions in some eating disorders (eg, anorexia nervosa). Stimulants like lisdexamfetamine...

Psilocybin Treatment as an Adjunct to Cognitive Behavioral Therapy for Eating Disorders: Therapeutic Rationale & Considerations for Protocol Development

Preprints.org December 19, 2025 Elena Koning, Susan Gamberg, Aaron Keshen preprint

Eating disorders (ED) remain challenging to treat, with high dropout and low remission rates in cognitive-behavioral therapy for EDs (CBT-ED). Psilocybin treatment (PT) demonstrates therapeutic potential to enhance CBT-ED by exerting several neurobiological, psychological, and experiential effects (e.g., antidepressant, neuroplasticity, emotional openness) that are hypothesized to increase...

Why psychedelic-assisted therapy studies in eating disorders risk missing the mark on outcomes: a phenomenological psychopathology perspective.

J Eat Disord September 2, 2025 Elena Koning, Riccardo Miceli Mcmillan, Aaron Keshen et al. 3 citations

Why psychedelic-assisted therapy studies in eating disorders risk missing the mark on outcomes: a phenomenological psychopathology perspective.

Psychedelics and the treatment of eating disorders: considerations for future research and practice.

J Eat Disord October 22, 2024 Emilie Lacroix, Karsten Fatur, Phillipa Hay et al. 12 citations

Recent trials have shown promising results for the use of psychedelic-assisted therapies in treating severe refractory psychiatric illnesses, and there has been growing interest in examining the effectiveness of these therapies in treating eating disorders. To move forward in a safe, ethically sound, and scientifically rigorous manner, the field must address critical considerations. In this...