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Nicolò Schifano

3 papers in the library · 26 citations · publishing 2025-2026

Papers

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Treatment and management approaches for ketamine misuse: A systematic review of medical interventions

Journal of Substance Use and Addiction Treatment July 1, 2026 Alessio Mosca, Stefania Chiappini, Andrea Miuli et al.

INTRODUCTION: Ketamine, initially developed as an anesthetic and now increasingly prescribed for treatment-resistant depression, is also widely misused in recreational contexts. Chronic ketamine use, often leading to dependence, has been associated with severe physical complications, including ulcerative cystitis and gastrointestinal dysfunction, as well as cognitive, affective, and psychotic...

DOI: 10.1016/j.josat.2026.210061 (opens in new tab) Ketamine Psychological intervention Medline Systematic review +2

Drugs Used in "Chemsex"/Sexualized Drug Behaviour-Overview of the Related Clinical Psychopharmacological Issues.

Brain Sciences April 22, 2025 Fabrizio Schifano, Stefania Bonaccorso, Davide Arillotta et al. 14 citations

Background: "Chemsex" involves the intake of a range of drugs (e.g., synthetic cathinones, gamma-hydroxybutyric acid/gamma-butyrolactone (GHB/GBL), ketamine, methamphetamine, "poppers", type V phosphodiesterase (PDE) inhibitors, MDMA/ecstasy, cocaine, cannabis, and occasionally a few other molecules as well, to enhance and prolong sexual experiences. This paper aims to provide an overview of...

DOI: 10.3390/brainsci15050424 (opens in new tab) Full text (opens in new tab) Substance abuse Sexual health Chemsex Drug addiction +4

Comparative safety of prescribed Esketamine and ketamine in relation to renal and urinary disorders: A pharmacovigilance perspective.

Progress in Neuro-Psychopharmacology and Biological Psychiatry January 10, 2025 Stefania Chiappini, Amira Guirguis, Nicolò Schifano et al. 12 citations

Intranasal esketamine, approved with oral antidepressants for adults with treatment-resistant depression (TRD), is the S-enantiomer of ketamine and has higher potency and affinity for N-Methyl-d-Aspartate receptors. Administered intranasally, it offers rapid absorption and onset, essential for severe depressive symptoms or suicidal impulses. Comparative studies on esketamine and ketamine's...

DOI: 10.1016/j.pnpbp.2024.111213 (opens in new tab) Full text (opens in new tab) S-ketamine Pharmacovigilance Urological safety Drug surveillance +5