Methylone and MDMA Pharmacokinetics Following Controlled Administration in Humans
International Journal of Molecular Sciences November 23, 2022 Lourdes Poyatos, Alfredo Fabrizio Lo Faro, Diletta Berardinelli et al. 22 citations
The aim of this study is to define, for the first time, human methylone and HMMC plasma pharmacokinetics following controlled administration of 50–200 mg methylone to 12 male volunteers. A new LC-MS/MS method was validated to quantify methylone, MDMA, and their metabolites in plasma. The study was a randomized, cross-over, double-blinded and placebo-controlled study, with a total of 468 plasma...