Inés Peraile

2 papers in the library · 44 citations · publishing 2009-2010

Papers

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Evidence that MDMA (‘ecstasy’) increases cannabinoid CB2 receptor expression in microglial cells: role in the neuroinflammatory response in rat brain

Journal of Neurochemistry January 12, 2010 Elisa Torres, María Dolores Gutiérrez‐lópez, Érika Borcel et al. 44 citations

J. Neurochem. (2010) 10.1111/j.1471‐4159.2010.06578.x Abstract 3,4‐Methylenedioxymethamphetamine (MDMA, ‘ecstasy’) produces selective long‐lasting serotonergic neurotoxicity in rats. The drug also produces acute hyperthermia which modulates the severity of the neurotoxic response. In addition, MDMA produces signs of neuroinflammation reflected as microglial activation and an increase in the...

DOI: 10.1111/j.1471-4159.2010.06578.x MDMA Ecstasy Serotonergic Neurotoxicity +7

Dopamine transporter down-regulation following repeated cocaine: implications for 3,4-methylenedioxymethamphetamine-induced acute effects and long-term neurotoxicity in mice.

British Journal of Pharmacology December 10, 2009 Inés Peraile, Elisa Torres, Andrea Mayado et al.

Background and purpose: 3,4-Methylenedioxymethamphetamine (MDMA) and cocaine are two widely abused psychostimulant drugs targeting the dopamine transporter (DAT). DAT availability regulates dopamine neurotransmission and uptake of MDMA-derived neurotoxic metabolites. We aimed to determine the effect of cocaine pre-exposure on the acute and long-term effects of MDMA in mice. Experimental...

DOI: 10.1111/j.1476-5381.2009.00522.x Full text Corpus striatum Cell membrane Animals Mice +12