Amphetamine-type central nervous system stimulants release norepinephrine more potently than they release dopamine and serotonin
Synapse 2000 Richard B Rothman, Michael H. Baumann, Christina M Dersch et al. 933 citations
A large body of evidence supports the hypothesis that mesolimbic dopamine (DA) mediates, in animal models, the reinforcing effects of central nervous system stimulants such as cocaine and amphetamine. The role DA plays in mediating amphetamine-type subjective effects of stimulants in humans remains to be established. Both amphetamine and cocaine increase norepinephrine (NE) via stimulation of...