3,4‐Methylenedioxymethamphetamine, mephedrone, and &bgr;‐phenylethylamine release dopamine from the cytoplasm by means of transporters and keep the concentration high and constant by blocking reuptake
European Journal of Pharmacology October 1, 2018 G. Zsilla, Daniella E Hegyi, M. Baranyi et al.
ABSTRACT The addiction‐related behavioural effects of drugs of abuse are mediated by the mesocorticolimbic monoamine systems. We investigated the effects of 3,4‐methylenedioxymethamphetamine (MDMA), mephedrone, &bgr;‐phenylethylamine (&bgr;‐PEA) methylphenidate (MPH) on dopamine release from mouse perfused nucleus accumbens and prefrontal cortex slices. The fractional release of [3H]‐dopamine...