Charles R. Ashby

2 papers in the library · 57 citations · publishing 1996-2000

Papers

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Enhancement of conditioned place preference response to cocaine in rats following subchronic administration of 3,4-methylenedioxymethamphetamine (MDMA)

Synapse February 1, 2000 Bryan Horan, Eliot L. Gardner, Charles R. Ashby 50 citations

In this study, we measured conditioned place preference (CPP) responses to cocaine following subchronic administration of the recreationally abused drug (+/-)-3,4-methylenedioxymethamphetamine (MDMA, "ecstasy") in male Sprague-Dawley rats. Animals were given either vehicle (1 ml/kg of distilled water, s.c.) or MDMA (20 mg/kg, s.c.) twice a day for 4 consecutive days. Two weeks later, CPP...

DOI: 10.1002/(sici)1098-2396(200002)35:2<160::aid-syn9>3.0.co;2-o MDMA Ecstasy Addiction Conditioned place preference +7

Examination of the action of 3,4-methylenedioxymethamphetamine on rat A10 dopamine neurons

Synapse May 1, 1996 Andrew N. Gifford, Yoshio Minabe, Alon Toor et al. 7 citations

Extracellular single cell recording was used to examine the effect of intravenous administration of (-), (+), and (+/-)-3,4-methylenedioxymethamphetamine (MDMA) on A10 dopamine (DA) neurons in chloral hydrate anesthetized male rats. Both (+/-)-MDMA and (+)-MDMA inhibited the firing rate of most (79%) A10 DA cells. By contrast, (-)-MDMA induced either no effect or a slight increase in the firing...

DOI: 10.1002/(sici)1098-2396(199605)23:1<52::aid-syn6>3.0.co;2-g