Examination of the action of 3,4-methylenedioxymethamphetamine on rat A10 dopamine neurons
Synapse May 1, 1996 Andrew N. Gifford, Yoshio Minabe, Alon Toor et al. 7 citations
Extracellular single cell recording was used to examine the effect of intravenous administration of (-), (+), and (+/-)-3,4-methylenedioxymethamphetamine (MDMA) on A10 dopamine (DA) neurons in chloral hydrate anesthetized male rats. Both (+/-)-MDMA and (+)-MDMA inhibited the firing rate of most (79%) A10 DA cells. By contrast, (-)-MDMA induced either no effect or a slight increase in the firing...