ChemRxiv
March 2, 2026
William Charles Hosie, Artem Pyrozhok, Massimo Filgiomeni et al.
Clinical trials of psychedelics have shown preliminary promise for the treatment of psychiatric conditions such as major depressive disorder, substance use disorder, and treatment resistant depression.The most common psychedelic administration routes explored so far include intravenous injection, heated vapor inhalation, or a simple buffered salt solution administered to the nasal cavity.Given...
Advanced Therapeutics
October 5, 2025
William Charles Hosie, Abhinandan Banerjee, Mary A. Egbuta et al.
Abstract Nanoformulation is often used to improve the solubility and uptake of bioactives; however, it also protects sensitive bioactives from chemical decomposition. A class of biocompatible emulsifiers created by conjugating hemp protein with green tea polyphenols is reported. A simple pH‐assisted coupling protocol is employed to synthesize covalent and non‐covalent conjugates, which are then...
ChemRxiv
February 27, 2025
William Charles Hosie, Mary Augustina Egbuta, Kasra Razmkhah et al.
Nanoformulation is often used to improve the solubility and uptake of bioactives; however, it also protects sensitive bioactives from chemical decomposition. We report a class of biocompatible emulsifiers created by conjugating hemp protein with green tea polyphenols. A simple pH-assisted coupling protocol was employed to synthesize covalent and non-covalent conjugates, which were then used to...
Journal of Psychoactive Drugs
January 29, 2025
Carrie Cuttler, Amanda Stueber, Jonathan J. Simone et al.
3 citations
The ever-changing landscape surrounding legality and accessibility of psychedelics and their increasing popularity make it imperative to better understand the nature of psychedelic use by the general population. To this end, 1,486 eligible respondents (Mage = 29.58, 67.1% male) residing in the United States completed an online survey designed to assess the types of psychedelics used, methods of...