3 papers in the library · 26 citations · publishing 2020-2026
Transl Psychiatry May 29, 2026 Justyna K. Hinchcliffe, Katie Kamenish, Julia M. Bartlett et al.
Differences in how NMDA antagonists modulate negative affective biases in male rats may serve as a predictor of clinical efficacy in major depressive disorder.
Science Translational Medicine January 10, 2024 Katie Kamenish, Roberto Arban, Aslihan Selimbeyoglu et al. 26 citations
How rapid-acting antidepressants (RAADs), such as ketamine, induce immediate and sustained improvements in mood in patients with major depressive disorder (MDD) is poorly understood. A core feature of MDD is the prevalence of cognitive processing biases associated with negative affective states, and the alleviation of negative affective biases may be an index of response to drug treatment....
bioRxiv (Cold Spring Harbor Laboratory) January 23, 2020 Ca Hales, Jm Bartlett, Roberto Arban et al. preprint
Abstract Major Depressive Disorder is a significant and costly cause of global disability. Until the discovery of the rapid acting antidepressant (RAAD) effects of ketamine, treatments were limited to drugs that have delayed clinical benefits. The mechanism of action of ketamine is currently unclear but one hypothesis is that it may involve neuropsychological effects mediated through modulation...