Frontiers in Psychology
February 14, 2024
Caspar Montgomery, Timo Torsten Schmidt, Ioanna Amaya
13 citations
Flicker light stimulation (FLS), a non-pharmacological method that induces altered states of consciousness (ASCs) and hallucination-like phenomena, can enhance emotional responses to music. In a study with twenty participants, listening to emotionally evocative music while undergoing FLS significantly increased reported music-evoked emotion, particularly emotions related to “Joyful Activation.” The intensity of the FLS experience correlated with higher levels of emotional arousal. These results suggest that FLS may serve as a method for inducing ASCs and that visual stimulation can interact with music-evoked emotion, paralleling effects seen with classic psychedelics like LSD.
Network neuroscience (Cambridge, Mass.)
January 1, 2025
Ioanna Amaya, Till Nierhaus, Timo T Schmidt
Rhythmic flicker light stimulation at 10 Hz reliably induces transient visual hallucinations in healthy people, while arrhythmic flicker does so less. Using fMRI, rhythmic flicker produced stronger activation in higher order visual cortices and selectively increased connectivity between ventroanterior thalamic nuclei and those cortices, compared to arrhythmic control. The strength of this connectivity correlated positively with the subjective intensity of hallucinations. Because the ventroanterior thalamus and higher order visual areas do not receive primary visual inputs, the findings suggest the thalamus coordinates cortical activity to generate hallucinatory experiences, offering insight into pathological hallucinations.
December 13, 2024
Trevor Hewitt, Ioanna Amaya, Romy Beauté et al.
preprint
Exposure to rapid and bright stroboscopic light can induce vivid visual hallucinations of color and geometric forms, a phenomenon first documented by Purkinje over 200 years ago. Despite centuries of scientific, therapeutic, and cultural interest, fundamental questions remain about its phenomenology, physiological origins, and potential clinical applications. This narrative review summarizes the historical research on stroboscopic light stimulation, its use in recreational and lay-therapeutic settings, and discusses the phenomenology of these experiences. It also examines current perspectives on the neural mechanisms that may underlie stroboscopically induced experiences and outlines directions for future research.
Neuroscience of Consciousness
January 1, 2025
Trevor Hewitt, Ioanna Amaya, Romy Beauté et al.
Exposure to rapid, bright stroboscopic light has been known for over 200 years to induce vivid visual hallucinations of color and geometric shapes. This narrative review summarizes the history of research on stroboscopic light stimulation (SLS), its recreational and lay-therapeutic uses, the phenomenology of the experiences it produces, and current understanding of potential neural mechanisms. Despite progress, fundamental questions remain about the full characterization of its phenomenology, its precise physiological origins, the conditions under which it leads to altered states of consciousness, and possible clinical applications.
Imaging neuroscience (Cambridge, Mass.)
January 1, 2023
Ioanna Amaya, Marianna E. Schmidt, Marie T Bartossek et al.
Flicker light stimulation (FLS) induces hyperconnectivity between the lateral geniculate nucleus (LGN) and early visual areas, as well as proximal upstream areas of the ventral visual stream (e.g., hV4, VO1). An exploratory analysis indicates that higher-order thalamic nuclei, such as the anterior and mediodorsal nuclei, are strongly affected by FLS, with connectivity changes to upstream cortical visual areas directly reflecting a frequency-dependent increase in experienced visual phenomena. These findings help identify specific thalamocortical interactions involved in the emergence of visual hallucinations.