A suite of engineered mice for interrogating psychedelic drug actions
bioRxiv (Cold Spring Harbor Laboratory) September 26, 2023 Yi-Ting Chiu, Wei Wang, Pierre Llorach et al. 15 citations preprint
ABSTRACT Psychedelic drugs like lysergic acid diethylamide (LSD) and psilocybin have emerged as potentially transformative therapeutics for many neuropsychiatric diseases, including depression, anxiety, post-traumatic stress disorder, migraine, and cluster headaches. LSD and psilocybin exert their psychedelic effects via activation of the 5-hydroxytryptamine 2A receptor (HTR2A). Here we provide...