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Guy Wallis

4 papers in the library · 511 citations · publishing 2005-2010

Papers

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Psilocybin slows binocular rivalry switching through serotonin modulation

Journal of Vision March 19, 2010 Olivia Carter, John D. Pettigrew, Felix Hasler et al. 3 citations

Binocular rivalry refers to the fluctuations in visual awareness/suppression that occur when different images are simultaneously presented to each eye. To explore the role of serotonin (5-HT) in binocular rivalry, this study investigated the affects of the hallucinogenic 5-HT1A&2A receptor agonist psilocybin (the active compound in “magic mushrooms”), alone and after pretreatment with the...

Psilocybin links binocular rivalry switch rate to attention and subjective arousal levels in humans

Psychopharmacology September 13, 2007 Olivia Carter, Felix Hasler, John D. Pettigrew et al. 150 citations

RationaleBinocular rivalry occurs when different images are simultaneously presented to each eye. During continual viewing of this stimulus, the observer will experience repeated switches between visual awareness of the two images. Previous studies have suggested that a slow rate of perceptual switching may be associated with clinical and drug-induced psychosis.ObjectivesThe objective of the...

Using Psilocybin to Investigate the Relationship between Attention, Working Memory, and the Serotonin 1A and 2A Receptors

Journal of Cognitive Neuroscience October 1, 2005 Olivia Carter, David C. Burr, John D. Pettigrew et al. 236 citations

Abstract Increasing evidence suggests a link between attention, working memory, serotonin (5-HT), and prefrontal cortex activity. In an attempt to tease out the relationship between these elements, this study tested the effects of the hallucinogenic mixed 5-HT1A/2A receptor agonist psilocybin alone and after pretreatment with the 5-HT2A antagonist ketanserin. Eight healthy human volunteers were...

Modulating the Rate and Rhythmicity of Perceptual Rivalry Alternations with the Mixed 5-HT2A and 5-HT1A Agonist Psilocybin

Neuropsychopharmacology January 26, 2005 Olivia Carter, John D. Pettigrew, Felix Hasler et al. 122 citations

Binocular rivalry occurs when different images are presented simultaneously to corresponding points within the left and right eyes. Under these conditions, the observer's perception will alternate between the two perceptual alternatives. Motivated by the reported link between the rate of perceptual alternations, symptoms of psychosis and an incidental observation that the rhythmicity of...