Psychedelics have robust effects on acute brain function and long-term behavior but whether they also cause enduring functional and anatomical brain changes is largely unknown. In an exploratory, placebo-controlled, within-subjects, electroencephalography (EEG), and magnetic resonance imaging (MRI) study in 28 healthy, entirely psychedelic-naive participants, anatomical and functional brain...
5-Methoxy-N,N-dimethyltryptamine (5-MeO-DMT) is a psychedelic gaining interest as a potential mental health treatment. However, a poorly characterized phenomenon termed reactivation (similar to "flashbacks") is commonly reported with 5-MeO-DMT use and merits investigation. This study examined the prevalence, predictors, and emotional valence of reactivations among Spanish-speaking individuals....