Posttraumatic stress disorder (PTSD) is a chronic and disabling condition and identifying beneficial therapies is timely and important. We aimed to estimate the efficacy of 3,4-methylenedioxymethamphetamine-assisted therapy (MDMA-AT) compared with control on clinical and functional outcomes in PTSD. A PRISMA-compliant search (PROSPEROCRD42022353261) up to August 14, 2025, covered nine databases...
BACKGROUND: The effectiveness of mindfulness-based programs in cultivating a sense of well-being has been demonstrated in many populations globally. However, mindfulness research is lacking in low socioeconomic contexts. This study explored how a mindfulness-based program may be adapted to be feasible, acceptable, and accessible to participants in a low socioeconomic setting in Cape Town, South...
OBJECTIVE: Large epidemiological surveys conducted in the developed world have found rates of psychotic symptoms in the general population to be as high as 10-28%. However, there are few data available from developing countries, including African countries, on the prevalence and correlates of psychotic symptoms. This study investigates the prevalence and correlates of psychotic symptoms (ie...
Jacqueline Samantha Womersley, Gabriela Iacovou, Yumna Kathrada et al.
preprint
Interest in psychedelic treatments for mental health conditions is growing. Health care professionals will be key in the implementation, recommendation, and administration of psychedelic-assisted therapy (PAT) if and when it is approved for clinical use, making their knowledge, attitudes, and perceptions (KAPs) central to successful translation into practice. We conducted a scoping review of...